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Results for “Roche”

A Phase III Study to Evaluate the Port Delivery System With Ranibizumab Compared With Monthly Ranibizumab Injections in Participants With Wet Age-Related Macular DegenerationCompleted
NCT03677934Phase 3Updated Oct 4, 2022
Sponsor: Hoffmann-La Roche
Neovascular Age-Related Macular Degeneration
United States
A Study of RO7293583 in Participants With Unresectable Metastatic Tyrosinase Related Protein 1 (TYRP1)-Positive MelanomasCompleted
NCT04551352Phase 1Updated Oct 3, 2022
Sponsor: Hoffmann-La Roche
Cutaneous Melanoma · Uveal Melanoma · Mucosal Melanoma
United States, Australia, Belgium, Canada, Denmark +1 more
Atezolizumab Immunotherapy, in Immunotherapy Naive Patients With Urinary Tract Squamous Cell Carcinoma (UTSCC).Unknown
NCT05038657Phase 2Updated Oct 3, 2022
Sponsor: University Hospital Southampton NHS Foundation Trust
Squamous Cell Carcinoma · Urinary Tract Cancer
United Kingdom
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation.Completed
NCT04623242Phase 2, Phase 3Updated Sep 22, 2022
Sponsor: Washington University School of Medicine
Alzheimers Disease · Dementia · Alzheimers Disease, Familial
United States, Australia, Canada, France, Ireland +3 more
A Study of Cobimetinib Plus Atezolizumab Versus Pembrolizumab in Participants With Previously Untreated Advanced BRAFv600 Wild-Type MelanomaTerminated
NCT03273153Phase 3Updated Sep 21, 2022
Sponsor: Hoffmann-La Roche
Advanced BRAFV600 Wild-type Melanoma
United States, Australia, Belgium, Brazil, France +10 more
Study to Assess Adverse Events and the Movement of Oral Venetoclax Tablet Through the Body of Female Participants Aged 18-75 Years With Impaired Renal FunctionCompleted
NCT04810598Phase 1Updated Sep 16, 2022
Sponsor: AbbVie
Renal Impairment · Renal Disease
United States
Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid TumorsCompleted
NCT02639546Phase 1, Phase 2Updated Sep 16, 2022
Sponsor: Hoffmann-La Roche
Solid Tumors
United States, France, Germany, Israel, Italy +2 more
Prospective Cohort for Early Detection of Liver CancerRecruiting
NCT05541601N/AUpdated Sep 15, 2022
Sponsor: University of Oxford
Cirrhosis · Hepatocellular Carcinoma
United Kingdom
The Detection of Small Early Liver Cancer With Natural History Follow upRecruiting
NCT05534906N/AUpdated Sep 10, 2022
Sponsor: University of Oxford
Hepatocellular Carcinoma
United Kingdom
A Study to Investigate the Safety and Efficacy of Atezolizumab in Previously-Treated Patients With Locally Advanced or Metastatic Non-Small Cell Lung CancerCompleted
NCT03922997Phase 3Updated Sep 9, 2022
Sponsor: Hoffmann-La Roche
Non-small Cell Lung Cancer
China
A Study To Assess Distribution Of RO7248824 In The Central Nervous System Following Single Intrathecal Doses Of [89zr] Labeled RO7248824 In Healthy Male ParticipantsCompleted
NCT04863794Phase 1Updated Sep 8, 2022
Sponsor: Hoffmann-La Roche
Angelman Syndrome
Netherlands
AMH for the Identification of PCOM in PCOS DiagnosisUnknown
NCT05527353N/AUpdated Sep 2, 2022
Sponsor: Oulu University Hospital
Polycystic Ovary Syndrome
Finland
The International Diabetes Closed Loop (iDCL) Trial: Clinical Acceptance of the Artificial Pancreas (DCLP3 Extension)Completed
NCT03591354NAUpdated Aug 31, 2022
Sponsor: University of Virginia
Type 1 Diabetes Mellitus
United States
A Study to Investigate Intravenous Tocilizumab in Participants With Moderate to Severe COVID-19 PneumoniaCompleted
NCT04363736Phase 2Updated Aug 31, 2022
Sponsor: Hoffmann-La Roche
COVID-19 Pneumonia
United States
A Study of Atezolizumab (Tecentriq®) in Ministry of Food and Drug Safety (MFDS)-Approved Indication(s)Completed
NCT03232593N/AUpdated Aug 24, 2022
Sponsor: Hoffmann-La Roche
Urothelial Carcinoma · Carcinoma, Non-Small Cell Lung · Small Cell Lung Carcinoma · Triple Negative Breast Carcinoma
South Korea
Atezolizumab, Rituximab, Gemcitabine and Oxaliplatin in Patients With Relapsed or Refractory DLBCL Not Suitable for High-dose TherapyTerminated
NCT03422523Phase 2Updated Aug 22, 2022
Sponsor: University Hospital Southampton NHS Foundation Trust
Diffuse Large B Cell Lymphoma · Relapsed Diffuse Large B-Cell Lymphoma · Refractory Diffuse Large B-Cell Lymphoma
United Kingdom
Impact of Concomitant Genetic Alterations in EGFR Mutated Adenocarcinoma by NGS Analysis: A Multicenter StudyUnknown
NCT04122833N/AUpdated Aug 18, 2022
Sponsor: Konkuk University Medical Center
Adenocarcinoma of Lung · EGFR Activating Mutation
South Korea
Study to Explore the Mechanism of Acquired Immune Escape In Participants With Metastatic Cancer Progressing on CPI TherapyCompleted
NCT03333655Phase 4Updated Aug 12, 2022
Sponsor: Hoffmann-La Roche
Neoplasms
United States, France, South Korea, Spain, United Kingdom
A Study of Obinutuzumab (RO5072759) Plus Chemotherapy in Comparison With Rituximab Plus Chemotherapy Followed by Obinutuzumab or Rituximab Maintenance in Patients With Untreated Advanced Indolent Non-Hodgkin's Lymphoma (GALLIUM)Completed
NCT01332968Phase 3Updated Aug 11, 2022
Sponsor: Hoffmann-La Roche
Non-Hodgkin's Lymphoma
United States, Australia, Belgium, Canada, China +13 more
Nordic Study in Newly Diagnosed Primary Central Nervous System (CNS) LymphomaCompleted
NCT01458730Phase 2Updated Aug 4, 2022
Sponsor: University of Aarhus
Central Nervous System Lymphoma
Denmark
Determination of Circulating Placental Biomarkers Levels to Predict the Pregnancy Outcome of First Trimester After IVF.Completed
NCT04387994N/AUpdated Aug 4, 2022
Sponsor: Instituto Valenciano de Infertilidade de Lisboa
Infertility, Female · First Trimester Spontaneous Abortion
Portugal
Crohn's Disease Endoscopic REmission Definition in an Objective WayCompleted
NCT03498625NAUpdated Aug 3, 2022
Sponsor: Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives
CD
Belgium, France
IN-HOspital Program to systematizE Chest Pain Protocol (IN-HOPE)Completed
NCT04756362N/AUpdated Aug 3, 2022
Sponsor: Hospital Samaritano Paulista
Chest Pain · Acute Coronary Syndrome
Brazil
Is the Endoscopic Remission Evaluation, Using the CREDO 1 Index / Score in CD Patients in Clinical Remission at Baseline, Predictive of Sustained Clinical Remission Using a 2-year Follow upUnknown
NCT03487900NAUpdated Aug 3, 2022
Sponsor: Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives
CD
Belgium, France
ADAPT Transcatheter Aortic Valve Intervention (TAVI & Chronic Total Occlusion Percutaneous Coronary Intervention (CTO PCI)Unknown
NCT05259241NAUpdated Jul 27, 2022
Sponsor: Erasmus Medical Center
Transcatheter Aortic Valve Replacement · Percutaneous Coronary Intervention
Netherlands

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