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Results for “United Kingdom”

A Phase 1 Trial of ZN-A-1041 Enteric Capsules or Combination in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Solid TumorsActive Not Recruiting
NCT05593094Phase 1, Phase 2Updated Aug 21, 2026
Sponsor: Hoffmann-La Roche
Advanced Solid Tumors · HER2-positive Breast Cancer
United States, Australia, France, Italy, New Zealand +2 more
Bicarbonate HD StudyRecruiting
NCT07779200N/AUpdated Aug 21, 2026
Sponsor: East and North Hertfordshire NHS Trust
Metabolic Acidosis · CKD on Hemodialysis Patients
United Kingdom
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)Recruiting
NCT07174336Phase 3Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Breast Neoplasms · Neoplasm Metastasis
United States, Argentina, Australia, Belgium, Brazil +14 more
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AMLRecruiting
NCT07007312Phase 3Updated Aug 20, 2026
Sponsor: Kura Oncology, Inc.
Acute Myeloid Leukemia (AML)
United States, Australia, Belgium, Canada, Czechia +11 more
A Study to Test Whether Nerandomilast Helps People With Systemic SclerosisRecruiting
NCT07497087Phase 3Updated Aug 20, 2026
Sponsor: Boehringer Ingelheim
Systemic Sclerosis
United States, Argentina, Australia, Austria, Belgium +40 more
A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and ProteinuriaRecruiting
NCT05457283Phase 3Updated Aug 20, 2026
Sponsor: Bayer
Chronic Kidney Disease · Proteinuria · Children
United States, Argentina, Australia, Austria, Belgium +27 more
A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus ErythematosusActive Not Recruiting
NCT05531565Phase 2, Phase 3Updated Aug 20, 2026
Sponsor: Biogen
Subacute Cutaneous Lupus Erythematosus · Chronic Cutaneous Lupus Erythematosus
United States, Argentina, Belgium, Brazil, Bulgaria +25 more
A Trial to Assess Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With AcromegalyCompleted
NCT04076462Phase 3Updated Aug 20, 2026
Sponsor: Camurus AB
Acromegaly
United States, Germany, Greece, Hungary, Italy +5 more
A Study to Test Long-term Treatment With Brigimadlin in People With Solid Tumours Who Took Part in a Previous Study With This MedicineActive Not Recruiting
NCT06619509Phase 2Updated Aug 20, 2026
Sponsor: Boehringer Ingelheim
Solid Tumours
United States, Argentina, Australia, Belgium, Canada +15 more
Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2Recruiting
NCT07227246Phase 3Updated Aug 20, 2026
Sponsor: Joseph Broderick, MD
Intracerebral Hemorrhage
United States, Canada, Germany, Japan, Spain +1 more
A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung CancerActive Not Recruiting
NCT04487080Phase 3Updated Aug 20, 2026
Sponsor: Janssen Research & Development, LLC
Carcinoma, Non-Small-Cell Lung
United States, Argentina, Australia, Belgium, Brazil +23 more
A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic RetinopathyActive Not Recruiting
NCT06321302Phase 2Updated Aug 20, 2026
Sponsor: Boehringer Ingelheim
Diabetic Retinopathy
United States, Germany, Hungary, Italy, Japan +4 more
A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC)Active Not Recruiting
NCT04008030Phase 3Updated Aug 20, 2026
Sponsor: Bristol-Myers Squibb
Metastatic Colorectal Cancer
United States, Argentina, Australia, Austria, Belgium +19 more
A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1)Active Not Recruiting
NCT06185764Phase 1, Phase 2Updated Aug 20, 2026
Sponsor: Vertex Pharmaceuticals Incorporated
Myotonic Dystrophy Type 1 (DM1)
United States, Australia, Belgium, Canada, France +5 more
A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF TherapyActive Not Recruiting
NCT05889182Phase 3Updated Aug 20, 2026
Sponsor: AbbVie
Hidradenitis Suppurativa
United States, Argentina, Australia, Austria, Belgium +32 more
A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)Recruiting
NCT06103864Phase 3Updated Aug 20, 2026
Sponsor: AstraZeneca
Breast Cancer
United States, Argentina, Australia, Brazil, Canada +19 more
The United Kingdom Facioscapulohumeral Muscular Dystrophy Patient RegistryRecruiting
NCT04001582N/AUpdated Aug 20, 2026
Sponsor: Newcastle University
Facioscapulohumeral Muscular Dystrophy
United Kingdom
Early Closure of Left Atrial Appendage for Patients With Atrial Fibrillation and Ischemic Stroke Despite Anticoagulation TherapyRecruiting
NCT05976685NAUpdated Aug 20, 2026
Sponsor: Insel Gruppe AG, University Hospital Bern
Ischemic Stroke · Atrial Fibrillation
Belgium, Germany, New Zealand, Spain, Switzerland +1 more
The Effect of 5-hydroxytryptophan on ADHD Traits and Eye MovementsRecruiting
NCT07777328NAUpdated Aug 20, 2026
Sponsor: University of Sheffield
Attention Deficit and Hyperactivity Disorder (ADHD) · Attention Deficit Hyperactivity Disorder in Adults · Attention Deficits
United Kingdom
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney DiseaseActive Not Recruiting
NCT06926660Phase 2Updated Aug 20, 2026
Sponsor: Boehringer Ingelheim
Chronic Kidney Disease
United States, Argentina, Australia, Belgium, Brazil +19 more
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular DiseaseRecruiting
NCT07064473Phase 3Updated Aug 20, 2026
Sponsor: Boehringer Ingelheim
Diabetes Mellitus, Type 2 · Hypertension · Cardiovascular Diseases
United States, Argentina, Australia, Austria, Belgium +46 more
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)Recruiting
NCT07107945Phase 3Updated Aug 20, 2026
Sponsor: Boehringer Ingelheim
Chronic Kidney Disease
United States, Argentina, Australia, Belgium, Canada +13 more
Long-Term Follow-up of Subjects Who Were Treated With ST-920Active Not Recruiting
NCT05039866N/AUpdated Aug 20, 2026
Sponsor: Sangamo Therapeutics
Fabry Disease · Fabry Disease, Cardiac Variant
United States, Australia, Canada, Germany, United Kingdom
A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative ColitisActive Not Recruiting
NCT04033445Phase 2, Phase 3Updated Aug 20, 2026
Sponsor: Janssen Research & Development, LLC
Ulcerative Colitis
United States, Argentina, Australia, Austria, Belgium +29 more
Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.Recruiting
NCT06382948Phase 3Updated Aug 20, 2026
Sponsor: MedSIR
Advanced Breast Cancer · ER-positive Breast Cancer · HER2-negative Breast Cancer · ESR1 Gene Mutation
Austria, Brazil, Czechia, France, Germany +4 more

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