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Phase I/II Study of CD5 CAR Engineered IL15-Transduced Cord Blood-Derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Hematological MalignancesRecruiting
NCT05110742Phase 1, Phase 2Updated Aug 20, 2026
Sponsor: M.D. Anderson Cancer Center
Hematological Malignancy
United States
Efficacy and Mechanisms of Escitalopram in Drug-Naïve First-Episode Major Depressive DisorderRecruiting
NCT07480525NAUpdated Aug 20, 2026
Sponsor: Peking University
Depression - Major Depressive Disorder
China
A Study of Romosozumab in People With Breast Cancer and OsteoporosisRecruiting
NCT07776613Phase 2Updated Aug 20, 2026
Sponsor: Memorial Sloan Kettering Cancer Center
Breast Cancer · Metastatic Breast Cancer (MBC)
United States
A Phase 2 Platform Study of Immunomodulatory Compounds in ICI-refractory Non-small Cell Lung CancerRecruiting
NCT07133425Phase 2Updated Aug 20, 2026
Sponsor: M.D. Anderson Cancer Center
Non-Small Cell Lung Cancer · ICI-refractory
United States
Pediatric Low Grade Glioma - MEKinhibitor TRIal vs ChemotherapyRecruiting
NCT05180825Phase 2Updated Aug 20, 2026
Sponsor: University Hospital, Strasbourg, France
Grade 1 Glioma · Mixed Glio-neuronal Tumors · Pleomorphic Xanthoastrocytoma
France
Pembrolizumab in Combination With Chemotherapy for the Treatment of Frail Hodgkin Lymphoma Patients Ineligible for Standard TreatmentRecruiting
NCT07275216Phase 2Updated Aug 20, 2026
Sponsor: City of Hope Medical Center
Classic Hodgkin Lymphoma
United States
Effectiveness of Live Motile Sperm Sorting Device on IVF Outcomes in Advanced Paternal AgeRecruiting
NCT07605182NAUpdated Aug 20, 2026
Sponsor: Vietnam Military Medical University
Male Infertility · Advanced Paternal Age · Assisted Reproductive Technology
Vietnam
Cerebrovascular Reactivity Measurements With High-Density Diffuse Optical TomographyRecruiting
NCT07776444NAUpdated Aug 20, 2026
Sponsor: Washington University School of Medicine
Sickle Cell Disease · Cerebral Stroke
United States
A Study of Eloralintide (LY3841136) in Participants With Obesity or OverweightRecruiting
NCT07738614Phase 1Updated Aug 20, 2026
Sponsor: Eli Lilly and Company
Obesity · Overweight
United States, Singapore
Phase 2 Trial of Zanzalintinib and Pembrolizumab in Select Subtypes of Advanced/Metastatic Soft-tissue SarcomaRecruiting
NCT07283731Phase 2Updated Aug 20, 2026
Sponsor: M.D. Anderson Cancer Center
Phase 2 · Zanzalintinib · Pembrolizumab · Advanced/Metastatic
United States
An Early-Stage Study in Multiple Clinics of How Afimkibart May Affect the Body's Processing of Medicines That Rely on Cytochrome P450 Enzymes in Participants With Ulcerative ColitisRecruiting
NCT07665723Phase 1Updated Aug 20, 2026
Sponsor: Hoffmann-La Roche
Active Ulcerative Colitis
United States, Belgium, Germany, Poland, United Kingdom
Exercise in Patients Undergoing Urologic SurgeryRecruiting
NCT03954678NAUpdated Aug 20, 2026
Sponsor: Emory University
Perioperative Complication
United States
Personalized Repetitive Transcranial Magnetic Stimulation (rTMS) in Cognitive Fluctuations of Dementia With Lewy Bodies (DLB): Proof of ConceptRecruiting
NCT05138588NAUpdated Aug 20, 2026
Sponsor: University Hospital, Strasbourg, France
Dementia With Lewy Bodies Diagnosis · Significant Cognitive Fluctuations in DLB
France
Ethnic and Gender Based Admittance Patterns in the ICURecruiting
NCT05513456N/AUpdated Aug 20, 2026
Sponsor: Karolinska Institutet
Critical Illness · Gender Equality · Discrimination, Sex · Discrimination, Racial
Sweden
Multiparametic Metabolic and Hypoxic PET/MRI for Disease Assessment in High Grade GliomaRecruiting
NCT05632562EARLY_Phase 1Updated Aug 20, 2026
Sponsor: University of Alabama at Birmingham
High Grade Glioma
United States
Physical Activity and Healthy Aging: Promoting Cardio-metabolic Capacity to Fight Chronic Inflammation and Improve Outcomes in Breast Cancer Patients (PhActHealth Study)Recruiting
NCT07776951NAUpdated Aug 20, 2026
Sponsor: University of Milan
Breast Cancer
Italy
Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC TrialRecruiting
NCT07388524Phase 3Updated Aug 20, 2026
Sponsor: National Cancer Institute (NCI)
Lung Non-Small Cell Carcinoma
United States
Ultrasound-guided Release of the Median Nerve at the Elbow in Patients With Lacertus SyndromeRecruiting
NCT06678646NAUpdated Aug 20, 2026
Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche
Median Nerve Entrapment
France
HERizon-Breast: A ctDNA-Guided Adaptive Study of Sequential Anti-HER2 Therapies and CNS Prophylaxis to Induce Long-Term RemissionRecruiting
NCT07459673Phase 2Updated Aug 20, 2026
Sponsor: Memorial Sloan Kettering Cancer Center
Breast Cancer · HER2-positive Breast Cancer · Breast Cancer Stage IV
United States
Exercise Performance on Ambient Air vs. Low-Flow Liquid Oxygen Therapy in Chronic Lung DiseasesRecruiting
NCT07777367NAUpdated Aug 20, 2026
Sponsor: Silvia Ulrich Somaini
Pulmonary Vascular Disease · Chronic Thromboembolic Pulmonary Hypertension (CTEPH) · Pulmonary Arterial Hypertension (PAH)
Switzerland
Cefazolin Antibiotic Prophylaxis in Ventricular Shunt Surgery: Determination of Cerebrospinal Fluid Concentration During Valve ImplantationRecruiting
NCT07067736NAUpdated Aug 20, 2026
Sponsor: University Hospital, Strasbourg, France
Hydrocephaly · CSF Shunts · Antibiotic Prophylaxis
France
A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL921 in Healthy Participants and Participants With Alzheimer's DiseaseRecruiting
NCT07758595Phase 1Updated Aug 20, 2026
Sponsor: Denali Therapeutics Inc.
Alzheimer's Disease · Healthy Participants
United Kingdom
Pacing of Left Bundle Branch Area and Atroventricular Node ablatIon in Patients With Symptomatic Atrial FibrillationRecruiting
NCT06699342NAUpdated Aug 20, 2026
Sponsor: Seoul National University Hospital
Atrial Fibrillation (AF)
South Korea
Head and Neck Cancer Study Project in the Geriatric PopulationRecruiting
NCT06998069Phase 3Updated Aug 20, 2026
Sponsor: Brown University
Head and Neck Neoplasms
United States
Effect of Pecha Kucha-Based Education on Symptom Management and Quality of Life in Patients Receiving ChemotherapyRecruiting
NCT07769931NAUpdated Aug 20, 2026
Sponsor: Istanbul Aydın University
Cancer · Neoplams
Turkey (Türkiye)

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