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Results for “Roche”

Characterization of Non-Steroidal Anti-Inflammatory Drug (NSAID) Intake in Rheumatoid Arthritis (RA) Participants on Tocilizumab (RoACTEMRA®) TreatmentCompleted
NCT03112213N/AUpdated Dec 13, 2018
Sponsor: Hoffmann-La Roche
Rheumatoid Arthritis
Germany
Relative Bioavailability of Gantenerumab Produced by G4 Process Versus G3 Process Following Subcutaneous (SC) Injection in Healthy ParticipantsCompleted
NCT03236844Phase 1Updated Dec 12, 2018
Sponsor: Hoffmann-La Roche
Healthy Participants
United States
A Study of Tocilizumab (RoActemra/Actemra) in Monotherapy or in Combination With Methotrexate or Other Non-Biologic DMARDs in Participants With Active Rheumatoid Arthritis and an Inadequate Response to Current Non-Biologic DMARD Therapy or the First Anti-TNF Biologic AgentCompleted
NCT02046603Phase 3Updated Dec 7, 2018
Sponsor: Hoffmann-La Roche
Rheumatoid Arthritis
United Kingdom
A Study of Avastin (Bevacizumab) in Combination With Fotemustine in Patients With Metastatic MelanomaCompleted
NCT01069627Phase 2Updated Dec 6, 2018
Sponsor: Hoffmann-La Roche
Malignant Melanoma
Italy
Study Investigating a Single Oral Dose of Fenebrutinib in Healthy VolunteersCompleted
NCT03596632Phase 1Updated Dec 6, 2018
Sponsor: Hoffmann-La Roche
Healthy Participants
United States
A Study of Rituximab (MabThera) Subcutaneous (SC) Versus Rituximab (MabThera) Intravenous in Participannts With Follicular Non-Hodgkin's LymphomaCompleted
NCT01200758Phase 3Updated Nov 27, 2018
Sponsor: Hoffmann-La Roche
Non-Hodgkin's Lymphoma
Australia, Belgium, Bosnia and Herzegovina, Brazil, Bulgaria +25 more
Study of the Pharmacokinetics and Safety of Trastuzumab Emtansine in Chinese Participants With Locally Advanced Inoperable or Metastatic HER2+ Breast CancerCompleted
NCT03153163Phase 1Updated Nov 23, 2018
Sponsor: Hoffmann-La Roche
Breast Neoplasms
China
A Study of Atezolizumab in Combination With Bevacizumab in Untreated Locally Advanced or Metastatic Clear Cell or Non-Clear Cell Renal Cell CarcinomaWithdrawn
NCT03693573Phase 3Updated Nov 15, 2018
Sponsor: Hoffmann-La Roche
Renal Cell Carcinoma
A Study of Subcutaneous Tocilizumab as Monotherapy and/or in Combination With Non-Biologic Disease Modifying Anti-Rheumatic Drugs (DMARDs) in Participants With Rheumatoid ArthritisCompleted
NCT01941095Phase 3Updated Nov 13, 2018
Sponsor: Hoffmann-La Roche
Rheumatoid Arthritis
Greece
A Study of Obinutuzumab (RO5072759) Induction in Patients With Relapsed/ Refractory Waldenström Macroglobulinemia, OBI-1Unknown
NCT03679455Phase 2Updated Nov 13, 2018
Sponsor: Polish Myeloma Consortium
Waldenstrom Macroglobulinemia
Poland
Disease Characteristics, Treatment Patterns and Clinical Outcomes in Patients With Newly Diagnosed Unresectable Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) in ChinaCompleted
NCT02458651N/AUpdated Nov 9, 2018
Sponsor: Hoffmann-La Roche
Non-Small Cell Lung Cancer, Lung Cancer, Cancer
China
A Study of Alectinib (RO5424802) in Participants With Non-Small Cell Lung Cancer Who Have Anaplastic Lymphoma Kinase (ALK) Mutation and Failed Crizotinib TreatmentCompleted
NCT01801111Phase 1, Phase 2Updated Nov 2, 2018
Sponsor: Hoffmann-La Roche
Non-Small-Cell Lung Carcinoma
United States, Australia, Belgium, Denmark, France +11 more
A Study of Tocilizumab (RoActemra) in Tocilizumab-Naive Participants With Rheumatoid Arthritis and Inadequate Response to Non-Biologic Disease-Modifying Antirheumatic Drugs (DMARDs) and/or Biologic TherapyCompleted
NCT02001987Phase 3Updated Nov 2, 2018
Sponsor: Hoffmann-La Roche
Rheumatoid Arthritis
France
A Study of Erlotinib in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor MutationsCompleted
NCT01260181Phase 2Updated Oct 31, 2018
Sponsor: Hoffmann-La Roche
Non-Squamous Non-Small Cell Lung Cancer
Portugal
Cardiopulmonary Exercise Testing in Interstitial Lung DiseaseCompleted
NCT02636452N/AUpdated Oct 29, 2018
Sponsor: Wissenschaftliches Institut Bethanien e.V
Interstitial Lung Disease
Germany
CINtec PLUS Triage in HPV Primary ScreeningUnknown
NCT03721484NAUpdated Oct 26, 2018
Sponsor: Western Health and Social Care Trust
Cervical Cancer
United Kingdom
Efficacy of FOLFOX+Bevacizumab in Combination With Irinotecan in the Treatment of Metastatic Colorectal CancerCompleted
NCT01321957Phase 2Updated Oct 25, 2018
Sponsor: Martin-Luther-Universität Halle-Wittenberg
Metastatic Colorectal Cancer
Germany
PEDS-C: Pegylated Interferon +/- Ribavirin for Children With Hepatitis CCompleted
NCT00100659Phase 3Updated Oct 24, 2018
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Hepatitis C
United States
A Study Evaluating Slow Response/Non-Rapid Response in Patients With Chronic Hepatitis C, Genotype 1, 2, 3 & 4 Treated With Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin)Completed
NCT01429792Phase 4Updated Oct 23, 2018
Sponsor: Hoffmann-La Roche
Hepatitis C, Chronic
Israel
A Dose Finding and Expansion Study of RO7051790 Administered Orally in Participants With Relapsed, Extensive-Stage Disease Small Cell Lung Cancer (ED SCLC)Completed
NCT02913443Phase 1Updated Oct 19, 2018
Sponsor: Hoffmann-La Roche
Small Cell Lung Cancer
United States, Canada, Denmark, France, Spain
A Study of the Efficacy and Safety of Tocilizumab for Confirmed Rheumatoid Arthritis (RA) Participants in Clinical PracticeTerminated
NCT02616328N/AUpdated Oct 18, 2018
Sponsor: Hoffmann-La Roche
Rheumatoid Arthritis
Saudi Arabia
Comparing Self Monitored Blood Glucose (SMBG) to Continuous Glucose Monitoring (CGM) in Type 2 DiabetesCompleted
NCT01237301NAUpdated Oct 17, 2018
Sponsor: HealthPartners Institute
Type 2 Diabetes
United States
A Pharmacokinetic/Pharmacodynamic Study of Oseltamivir in Immunocompromised Children With Confirmed Influenza InfectionCompleted
NCT01715909Phase 1Updated Oct 16, 2018
Sponsor: Hoffmann-La Roche
Influenza
United States, Belgium, Brazil, Canada, Chile +10 more
Atezolizumab Monotherapy vs Atezolizumab Plus Cobimetinib in Liver Metastases From Colorectal CancerWithdrawn
NCT03340558Phase 2Updated Oct 9, 2018
Sponsor: Niharika Mettu
Metastatic Colorectal Cancer
United States
A Study of Vanucizumab (RO5520985) Alone or in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid TumorsCompleted
NCT01688206Phase 1Updated Oct 5, 2018
Sponsor: Hoffmann-La Roche
Neoplasms
Belgium, France, Spain

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