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Characterization of Non-Steroidal Anti-Inflammatory Drug (NSAID) Intake in Rheumatoid Arthritis (RA) Participants on Tocilizumab (RoACTEMRA®) Treatment
Characterization of Non-Steroidal Anti-Inflammatory Drug (NSAID) Intake in Rheumatoid Arthritis (RA) Participants on Tocilizumab (RoACTEMRA®) Treatment

NCT03112213

CompletedN/A

Sponsor: Hoffmann-La Roche

Conditions: Rheumatoid Arthritis

Interventions: Tocilizumab, NSAIDs

Countries: Germany

This nationwide, multicenter, single arm, prospective, non-interventional study will evaluate the quantitative pattern of NSAID use and the impact of treatment with tocilizumab on NSAID use in a representative cohort of participant with moderate to severe active RA who have either responded inadequately to, or who were intolerant to previous therapy with one or more synthetic disease modifying anti-rheumatic drug (sDMARD), and for whom the physician has made the individual decision to initiate tocilizumab (subcutaneous \[SC\] or intravenous \[IV\]) as first biological disease modifying anti-rheumatic drug (DMARD) therapy according to the summary of product characteristics (SPC).

Eligibility overview

Sex: ALL

Age: 18 Years to

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria
Inclusion Criteria:

* Participants with moderate to severe active RA who have either responded inadequately to, or who were intolerant to, previous therapy with one or more sDMARDs and for whom the physician has made the individual decision to be treated with tocilizumab (SC or IV)
* Current users of NSAIDs due to RA as assessed by the physician

Exclusion Criteria:

* Contraindications to treatment with tocilizumab as per SPC
* Prior therapy with tocilizumab
Locations (27)
  • Altenburg, Germany
  • Amberg, Germany
  • Bad Nauheim, Germany
  • Berlin, Germany
  • Berlin, Germany
  • Berlin, Germany
  • Berlin, Germany
  • Burghausen, Germany
  • Dresden, Germany
  • Güstrow, Germany
  • Halle, Germany
  • Hanover, Germany
  • Heidelberg, Germany
  • Magdeburg, Germany
  • Mansfeld, Germany
  • München, Germany
  • München, Germany
  • Neubrandenburg, Germany
  • Neuss, Germany
  • Neuss, Germany
  • Offenburg, Germany
  • Poppenbüttel, Germany
  • Püttlingen, Germany
  • Ratingen, Germany
  • Saarbrücken, Germany
  • Stuttgart, Germany
  • Ulm, Germany