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Results for “Roche”

Drug Treatment Validation of Functional Magnetic Resonance Imaging in Generalized Anxiety DisorderCompleted
NCT00662259Phase 4Updated Jul 25, 2019
Sponsor: University of California, San Diego
Generalized Anxiety Disorder
United States
BELOVA Data Collection: Safety and Efficacy of Frontline Bevacizumab Treatment in Participants With Ovarian Cancer 70 Years and OlderCompleted
NCT02393898N/AUpdated Jul 24, 2019
Sponsor: Hoffmann-La Roche
Ovarian Cancer
Belgium
A Study of Vemurafenib Adjuvant Therapy in Participants With Surgically Resected Cutaneous BRAF-Mutant MelanomaCompleted
NCT01667419Phase 3Updated Jul 23, 2019
Sponsor: Hoffmann-La Roche
Melanoma
United States, Argentina, Australia, Austria, Belgium +24 more
A Study to Assess Programmed Death Ligand-1 (PD-L1) Expression in Cytological Versus Histological Lung Cancer SpecimensCompleted
NCT03092739N/AUpdated Jul 23, 2019
Sponsor: Hoffmann-La Roche
Carcinoma, Non-Small-Cell Lung · Carcinoma, Small Cell
Czechia, Germany, Poland, Spain, Switzerland +1 more
An Extension Study of Onartuzumab in Participants With Solid Tumors on Study Treatment Previously Enrolled in a Company Sponsored StudyCompleted
NCT02488330Phase 3Updated Jul 23, 2019
Sponsor: Hoffmann-La Roche
Solid Tumor
France, Italy, Japan, Latvia, Russia +3 more
A Study to Assess the Feasibility of an E-Health System (ZEMY) Designed to Manage Symptoms in Participants With Breast Cancer Under Anti-Cancer TreatmentCompleted
NCT03558490Phase 2Updated Jul 22, 2019
Sponsor: Hoffmann-La Roche
Breast Cancer
France
A Study to Assess Hemoglobin Level Depending on the Comorbidity Index in Chronic Kidney Disease (CKD) Participants Not in Dialysis Treated With Methoxy Polyethylene Glycol-Epoetin Beta (COMETE)Completed
NCT01756612N/AUpdated Jul 15, 2019
Sponsor: Hoffmann-La Roche
Renal Anemia of Chronic Kidney Disease
France
A Study Evaluating Trastuzumab Emtansine Plus Pertuzumab Compared With Chemotherapy Plus Trastuzumab and Pertuzumab for Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast CancerCompleted
NCT02131064Phase 3Updated Jul 2, 2019
Sponsor: Hoffmann-La Roche
Breast Neoplasms
United States, Belgium, Canada, France, Germany +5 more
A Study Investigating the Efficacy and Safety of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular DegenerationTerminated
NCT02247479Phase 3Updated Jun 26, 2019
Sponsor: Hoffmann-La Roche
Geographic Atrophy
United States, Argentina, Australia, Austria, Belgium +14 more
A Phase IIa Study of Intravenous Rituximab in Pediatric Participants With Severe Granulomatosis With Polyangiitis (Wegener's) or Microscopic PolyangiitisCompleted
NCT01750697Phase 2Updated Jun 26, 2019
Sponsor: Hoffmann-La Roche
Granulomatosis With Polyangiitis
United States, Canada, France, Germany, Italy +3 more
A Study of The Effect of Altitude on Mircera (Methoxy Polyethylene Glycol-Epoetin Beta) Dose Requirements in Participants With Chronic Renal Anemia in Pre-Dialysis or DialysisCompleted
NCT01519947Phase 4Updated Jun 19, 2019
Sponsor: Hoffmann-La Roche
Anemia, Kidney Disease, Chronic
Mexico
A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid TumorsCompleted
NCT03362723Phase 1Updated Jun 19, 2019
Sponsor: Hoffmann-La Roche
Solid Tumors
United States, Canada
A Study to Assess the Impact of Speed and Site of Subcutaneous Injection on Pain, Tolerability, Safety, and Pharmacokinetics of Gantenerumab in Healthy ParticipantsCompleted
NCT02882009Phase 1Updated Jun 11, 2019
Sponsor: Hoffmann-La Roche
Healthy Volunteer
United States
Study to Evaluate Home Vision Testing in Participants Who Receive Ranibizumab (Lucentis®)Completed
NCT02420132N/AUpdated Jun 10, 2019
Sponsor: Hoffmann-La Roche
Macular Edema · Macular Degeneration
United States
A Study to Investigate the Tolerability of Subcutaneous (SC) Trastuzumab Administration in Participants With Human Epidermal Growth Factor Receptor 2 (HER2) Positive Early Breast Cancer (eBC) Using Either a Single-Use Injection Device or Manual AdministrationCompleted
NCT02194166Phase 3Updated Jun 10, 2019
Sponsor: Hoffmann-La Roche
Breast Cancer
Belarus, Kazakhstan
STEVIE: A Study of Vismodegib in Patients With Locally Advanced or Metastatic Basal Cell CarcinomaCompleted
NCT01367665Phase 2Updated Jun 6, 2019
Sponsor: Hoffmann-La Roche
Basal Cell Carcinoma
Argentina, Australia, Austria, Belgium, Bosnia and Herzegovina +32 more
A Study Evaluating the Safety and Efficacy of Venetoclax (GDC-0199) Plus Bendamustine + Rituximab (BR) in Comparison With BR or Venetoclax Plus Rituximab in Participants With Relapsed and Refractory Follicular Non-Hodgkin's Lymphoma (fNHL)Completed
NCT02187861Phase 2Updated Jun 5, 2019
Sponsor: Hoffmann-La Roche
Follicular Lymphoma
United States, Australia, Belgium, Canada, France +3 more
Safety and Efficacy of Bevacizumab in Combination With Carboplatin and Paclitaxel for Metastatic, Recurrent or Persistent Cervical CancerCompleted
NCT02467907Phase 2Updated Jun 3, 2019
Sponsor: Hoffmann-La Roche
Cervical Cancer
Argentina, Brazil, Bulgaria, Colombia, Costa Rica +13 more
A Study of Vemurafenib (Zelboraf) in Chinese Participants With BRAF V600 Mutation-Positive Unresectable or Metastatic MelanomaCompleted
NCT01910181Phase 1Updated May 29, 2019
Sponsor: Hoffmann-La Roche
Malignant Melanoma
China
A Long Term Extension Study of WA19926 (NCT01007435) of Tocilizumab (RoActemra/Actemra) in Participants With Early, Moderate to Severe Rheumatoid Arthritis (RA)Completed
NCT01668966Phase 3Updated May 13, 2019
Sponsor: Hoffmann-La Roche
Rheumatoid Arthritis
Brazil
Observational Study to Determine the Effectiveness and Safety of Vismodegib (Erivedge®) in Participants With Locally Advanced Basal Cell Carcinoma (laBCC)Completed
NCT02674009N/AUpdated May 13, 2019
Sponsor: Hoffmann-La Roche
Carcinoma, Basal Cell
Germany
Sequential Regimen of Bendamustin [B] Followed by GA101 and Ibrutinib [I] in CLL PatientsCompleted
NCT02345863Phase 2Updated May 8, 2019
Sponsor: German CLL Study Group
Chronic Lymphocytic Leucemia
Germany
An Observational Study on Long-Term Efficacy and Safety of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Rheumatoid Arthritis (FAct)Completed
NCT01483326N/AUpdated May 1, 2019
Sponsor: Hoffmann-La Roche
Rheumatoid Arthritis
Netherlands
Randomized Trial of Pegylated Interferon Alfa-2a Versus Hydroxyurea in Polycythemia Vera (PV) and Essential Thrombocythemia (ET)Completed
NCT01259856Phase 3Updated Apr 30, 2019
Sponsor: Ronald Hoffman
High Risk Polycythemia Vera · High Risk Essential Thrombocythemia
United States, France, Italy, United Kingdom
Expanded Access to RXDX-105 for Cancers With RET AlterationsNo Longer Available
NCT03052569N/AUpdated Apr 26, 2019
Sponsor: Hoffmann-La Roche
Cancers With RET Alterations
United States

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