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Intra-Prostatic Epinephrine Injection in Bipolar Transurethral Resection of Large Prostate: Exploring Its Role in Optimizing Surgical Outcomes

NCT07733167

RecruitingPhase 3

Sponsor: Benha University

Conditions: Intra-Prostatic Epinephrine Injection in Bipolar Transurethral Resection of Large Prostate

Interventions: TURP, Epinephrine

Countries: Egypt

Intra-Prostatic Epinephrine injection in Bipolar Transurethral resection of large prostate: Exploring Its Role in Optimizing Surgical Outcomes

Eligibility overview

Sex: MALE

Age: 40 Years to —

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* Indication for Prostate Surgery or Procedure - Patients undergoing transurethral resection of the prostate (TURP)
* Prostate from 80 to 100 gm
* Failed medical therapy

Exclusion Criteria:

* Uncontrolled Hypertension - Patients with significantly high blood pressure despite medication therapy.
* Unstable angina, recent myocardial infarction, arrhythmias, or severe heart failure.
* Significant Coagulopathy - Patients with bleeding disorders or on anticoagulants where excessive vasoconstriction may lead to tissue necrosis or inadequate perfusion
* Hyperthyroidism, Pheochromocytoma or Endocrine Disorders - Patients with catecholamine-secreting tumors or other conditions that can lead to excessive sympathetic stimulation.
* Treatment in the last 3 months with 5-alpha reductase inhibitors.
* Genitourinary cancer, urinary tract lithiasis, and urological surgery within the last 3 months

Locations (1)

Banhā, Qalyubia Governorate, Egypt