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A Study of Lung Cancer Risk

RecruitingN/A

Sponsor: Memorial Sloan Kettering Cancer Center

Conditions: Lung Cancer

Interventions: Questionnaire

Countries: United States

The researchers are doing this study to learn more about factors that may increase the risk of lung cancer in people who have never smoked. This information may help predict which people who have never smoked may be more likely to get lung cancer.

Eligibility overview

Sex: ALL

Age: 40 Years to 74 Years

Healthy volunteers: Yes

Study type: OBSERVATIONAL

Eligibility criteria

Criteria:

* Female at birth
* Age 40-74 years
* No smoking history

  * Participants must be never-smokers, defined as having smoked \<100 cigarettes in their lifetime
* Documentation of disease - case patients

  o Case patients must have pathologically confirmed primary lung adenocarcinoma. New and prevalent cases will be eligible. Case patients with a history of prior non-lung cancer will be eligible for the study unless actively being diagnosed or treated for another form of cancer at the time of enrollment.
* Criteria for control participants

  * Control participants must have no personal history of lung cancer, symptoms suspicious for lung cancer, or suspicious pulmonary nodules. Participants recruited as controls and found on imaging to have lesions suspicious for lung cancer will be excluded from analysis and followed prospectively. Data regarding these participants will be reported in a sensitivity analysis. Additional control participants will be recruited to ensure balanced age- and race-matched enrollment by frequency matching. Control participants with a history of prior non-lung cancer will be eligible for the study unless actively being diagnosed or treated for another form of cancer at the time of enrollment.

Locations (7)

Basking Ridge, New Jersey, United States
Middletown, New Jersey, United States
Montvale, New Jersey, United States
Commack, New York, United States
Harrison, New York, United States
New York, New York, United States
Uniondale, New York, United States