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Sponsor: Neuro Group XR Inc.
Conditions: Parkinson s Disease
Interventions: Immersive Virtual Reality, Non-Immersive Virtual Reality
Countries: Chile
Parkinson's disease commonly affects walking ability, balance, mobility, and cognitive function, increasing the risk of falls and reducing independence. Virtual reality (VR) has emerged as a promising rehabilitation tool, but the potential differences between immersive and non-immersive VR approaches remain unclear. This pilot randomized comparative study aims to evaluate the feasibility, safety, and preliminary effects of immersive virtual reality (IVR) and non-immersive virtual reality (NIVR) rehabilitation in individuals with Parkinson's disease. Participants will be assigned to either an immersive VR intervention using a head-mounted display or a non-immersive VR intervention using a tablet-based exergaming platform. Both interventions will be delivered over six weeks and will target gait, balance, mobility, motor-cognitive interaction, and functional performance. Outcomes will include gait parameters, functional mobility, freezing of gait, cognitive function, adherence, and safety. The findings will help determine whether different VR modalities produce distinct motor and cognitive responses and will inform the design of future larger clinical trials.
Sex: ALL
Age: 45 Years to 75 Years
Healthy volunteers: No
Study type: INTERVENTIONAL
Inclusion Criteria: * Age between 45 and 75 years. * Diagnosis of idiopathic Parkinson's disease. * Hoehn and Yahr stage between 1.5 and 4. * Ability to walk independently or with an assistive device (cane or walker). * Low to moderate fall risk, defined as a Timed Up and Go (TUG) score \<20 seconds. * Ability to provide written informed consent. Exclusion Criteria: * Diagnosis of other neurological or movement disorders. * Severe cognitive impairment, defined as a Montreal Cognitive Assessment (MoCA) score \<18. * Severe visual impairment not correctable with lenses. * History of epilepsy. * Uncontrolled psychiatric disorders. * Previous deep brain stimulation.
- La Serena, Chile