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Neural Basis of Human Working Memory

RecruitingNA

Sponsor: Vanderbilt University Medical Center

Conditions: Memory Disorders

Interventions: Neurocognitive Tasks, Ripple Neuromed Summit System

Countries: United States

This ClinicalTrials.gov entry corresponds to the Neural Basis of Human Working Memory protocol approved under Vanderbilt University Medical Center IRB #251231. This study investigates the neural activity underlying human working memory, via local field potential changes (macro level) and/or single neuronal spiking changes (micro level) from depth electrodes placed for invasive seizure monitoring. Subjects will complete neurocognitive tasks while neural recordings are collected. Some patients will complete neurocognitive tasks while stimulation is applied via depth electrodes. Further understanding the neural activity changes underlying normal and impaired working memory may help to identify novel diagnostic methods and treatments for impaired working memory and may support the use of stimulation for treatment of memory disorders.

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* Undergoing SEEG monitoring at Vanderbilt University Medical Center
* Age \>18
* English speaking

Exclusion Criteria:

* Age \<18
* Not able to complete questionnaires (unable to comprehend instructions or follow directions)

Locations (1)

Nashville, Tennessee, United States