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BÜHLMANN BAT (Basophil Activation Test) in Allergy Diagnosis (Exploratory Pilot Study)
BÜHLMANN BAT (Basophil Activation Test) in Allergy Diagnosis (Exploratory Pilot Study)

NCT07596303

CompletedN/A

Sponsor: Bühlmann Laboratories AG

Conditions: Allergy Testing, Peanut Allergies, Venom Allergy, House Dust Mite Allergy, Hazelnut Allergy

Countries: Germany

The goal of this exploratory pilot study is to generate early data needed for future validation studies of the automated BÜHLMANN BAT (Basophil activation test) assay. The main questions it aims to answer are: Does the BAT assay use the optimal allergen concentrations for stimulation, and how do its preliminary cut-offs perform in a real-world clinical scenario? Participants older than 1.5 years who are being evaluated for possible allergy sensitization will provide one additional blood tube during their routine blood draw as part of the regular medical care. The study involves only one visit and does not provide direct personal benefit.

Eligibility overview

Sex: ALL

Age: 18 Months to

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria
Inclusion Criteria:

* Individuals with diagnosis of a hypersensitivity / allergy to one of the 6 allergens, established according to common clinical practice

Exclusion Criteria:

* Pregnant women
* Children under the age of 18 months
* Individuals under therapy with Omalizumab or Rituximab
* Individuals with an allergic reaction less than two weeks before blood sample collection
* Individuals under therapy with BTK inhibitors
* Individuals receiving allergen specific immunotherapy (ASIT)
* Subjects with active infection and inflammatory conditions
* Patients who are unable to understand the study information and informed consent form in German
Locations (1)
  • München, Germany