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"Dexa vs Dexmedetomidine With Bupivacaine in TAP Block for Laparotomy Analgesia

RecruitingPhase 2, Phase 3

Sponsor: Sahiwal medical college sahiwal

Conditions: Pain, Postoperative, Opioid Use, Laparotomy

Interventions: Bupivacaine Hcl 0.25% Inj_#1, Bupivacaine Hcl 0.25% Inj_#2

Countries: Pakistan

Transversus abdominis plane block is a regional anesthetic technique which blocks the abdominal neural afferents by introducing local anesthetic into the neuro-fascial plane between the internal oblique and the transversus abdominis muscle and gives analgesia from the skin to parietal peritoneum. There are studies showing evidence of improved post operative analgesia with addition of adjuvants such as dexmedetomidine or dexamethasone in comparison with plane local anesthesia in terms of time to rescue analgesia and the overall quantity of analgesic used post operatively.

Eligibility overview

Sex: ALL

Age: 25 Years to 65 Years

Healthy volunteers: Yes

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* Patients undergoing laparotomy.
* Patients aged 25 to 65 years.
* Both genders.
* Patients with ASA Class I, II.

Exclusion Criteria:

* Patients who do not give consent.
* Patients with Comorbidities like DM, HTN, CKD, CLD.
* Patients with bleeding disorders.
* Infection at site of injection.
* Allergy to any drug, local anaesthetic, or other drugs used.
* Patients with polytrauma.

Locations (1)

Sahiwal, Punjab Province, Pakistan