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The Effects of High-Intensity Interval Training on Gait, Balance, and Cognitive Functions in Individuals With Multiple Sclerosis
The Effects of High-Intensity Interval Training on Gait, Balance, and Cognitive Functions in Individuals With Multiple Sclerosis

NCT07578740

Not Yet RecruitingNA

Sponsor: Hacettepe University

Conditions: Multiple Sclerosis, High-intensity Interval Training, Gait, Balance, Cognition

Interventions: Moderate-Intensity Continuous Training (MICT), High-Intensity Interval Training (HIIT)

Countries: Turkey (Türkiye)

This study aims to comparatively investigate the effects of low-volume High-Intensity Interval Training (HIIT) versus Moderate-Intensity Continuous Training (MICT) on gait, balance, cognitive functions, and neurovascular biomarkers (BDNF, VEGF) in individuals with Multiple Sclerosis (MS). This randomized controlled trial will be conducted at Hacettepe University, Faculty of Physical Therapy and Rehabilitation.

Eligibility overview

Sex: ALL

Age: 18 Years to

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria
Inclusion Criteria:

* Diagnosed with Multiple Sclerosis by a neurologist (Hacettepe University Hospitals, Neurology Outpatient Clinic)
* Age 18 years and older
* EDSS score between 0 and 4
* Score of 24 or above on the Standardized Mini Mental State Examination
* No relapse in the past 3 months
* Medically stable for at least 6 months

Exclusion Criteria:

• Any additional cardiopulmonary, neurological, or systemic disease other than MS
Locations (1)
  • Ankara, Turkey (Türkiye)