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Stimulant and Polysubstance Use, Inflammation, and Sex Effects on Myocardial Disease in HIV
Stimulant and Polysubstance Use, Inflammation, and Sex Effects on Myocardial Disease in HIV

NCT07461350

Enrolling By InvitationN/A

Sponsor: University of California, San Francisco

Conditions: HIV (Human Immunodeficiency Virus)

Countries: United States

This observational research study is studying how substance use impacts scarring and inflammation of the heart. This study involves one study visit for a cardiac MRI.

Eligibility overview

Sex: ALL

Age: 30 Years to —

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria
Inclusion Criteria:

\- Participants with and without HIV enrolled in the MACS/WIHS Combined Cohort Study (MWCCS) Atlanta, Baltimore, Bronx, and San Francisco study sites

Exclusion Criteria:

* Standard contraindications to MRI
* claustrophobia,
* metal implants,
* large body size (weight \>350 lbs or abdominal sagittal diameter \>70 cm),
* pregnancy)
* Gadolinium risk
* severe or uncontrolled asthma,
* visit day eGFR\<45 ml/min/1.73 m2;
* poor venous access
* pregnancy or lactation
Locations (4)
  • San Francisco, California, United States
  • Atlanta, Georgia, United States
  • Baltimore, Maryland, United States
  • The Bronx, New York, United States