NCT lookup

Pull any trial record directly from ClinicalTrials.gov.

Routine vs. Early Postpartum Depression Screening: A Pragmatic Clinical Trial

Not Yet RecruitingNA

Sponsor: Massachusetts General Hospital

Conditions: Postpartum Depression (PPD)

Interventions: Early PPD Screening

After having a baby, some women develop a condition called postpartum depression, or PPD, which can cause sadness, anxiety, and difficulty bonding with their newborn. Right now, most women aren't screened for PPD until about 6 to 8 weeks after giving birth, but this study wants to find out if checking earlier could help identify signs sooner. To test this, researchers will work with 428 women who deliver at an MGH hospital clinic and have no history of depression. Each woman will be randomly placed into one of two groups: one group will fill out a short depression questionnaire online at 2 to 3 weeks after delivery, while the other group will follow the usual process and complete the same questionnaire at their regular 6-week visit. The results will go to each woman's doctor, who will decide if any follow-up care is needed, just like they normally would. The study will follow each participant for 6 months after delivery to see whether earlier screening makes a difference.

Eligibility overview

Sex: FEMALE

Age: 18 Years to —

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

1. Live birth, term (≥37 weeks) delivery at Massachusetts General Hospital
2. Access to Patient Gateway, as to receive the electronic EPDS scale
3. Primary obstetric provider at MGH or its affiliated clinics
4. No recent history of depressive disorder as determined through diagnoses or medication use\*
5. Age ≥18 years old

Exclusion Criteria:

1. A diagnosis code in the EHR for major depressive disorder, bipolar disorder, or psychotic disorder within the year prior to delivery
2. Antidepressant, antipsychotic, or bipolar medication use within the year prior to delivery
3. Age \<18 years old