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Comprehensive Geriatric Assessment in Adults Aged 40 Years and Older Living With HIV

Not Yet RecruitingN/A

Sponsor: Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital

Conditions: Frailty, Sarcopenia

People living with HIV are experiencing longer life expectancy due to effective antiretroviral therapy; however, they may develop age-related conditions earlier than the general population. This prospective observational study aims to evaluate frailty, sarcopenia, nutritional status, cognitive function, and functional performance in adults aged 40 years and older living with HIV and to compare them with age- and sex-matched healthy controls.

Eligibility overview

Sex: ALL

Age: 40 Years to 99 Years

Healthy volunteers: Yes

Study type: OBSERVATIONAL

Eligibility criteria

Age ≥ 40 years

Confirmed diagnosis of HIV infection (for HIV group)

On stable antiretroviral therapy for at least 6 months (for HIV group)

HIV-negative status confirmed by medical history or testing (for control group)

Ability to provide informed consent

Exclusion Criteria:

Acute infection or hospitalization within the last 4 weeks

Known active malignancy under treatment

Severe psychiatric disorder interfering with assessment

Severe cognitive impairment preventing participation