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Lead Exposure and Multiple Sclerosis

Not Yet RecruitingN/A

Sponsor: Assiut University

Conditions: Multiple Sclerosis

1. To evaluate the effect of lead level on the pathogenesis of multiple sclerosis 2. Measure lead in blood sample of study groups 3. Estimate the expression level of DNA methyltransferase. 4. Evaluate oxidative stress markers, like MDA/8-OHdG 5. Measureδ-aminolevulinic acid 6. Correlate the clinical data of patients with biochemical markers

Eligibility overview

Sex: ALL

Age: 20 Years to 50 Years

Healthy volunteers: Yes

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

* patients aged20-50 years diagnosed MS patients according to Mc Donald criteria

Exclusion Criteria:

* other autoimmune disease Chronic renal or liver disease