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Periodontal Health Profile in Multiple Sclerosis Patients

Not Yet RecruitingN/A

Sponsor: Saglik Bilimleri Universitesi

Conditions: Multiple Sclerosis, Periodontitis

This study aims to evaluate the periodontal status of patients with Multiple Sclerosis (MS) through clinical, microbiological, and biochemical parameters. Multiple sclerosis and periodontal diseases are both chronic inflammatory conditions that may share common immunopathological pathways. The primary objective is to investigate the relationship between MS and periodontal health by comparing clinical measurements with the microbial composition and biochemical markers found in saliva samples of patients followed by the Neurology Department.

Eligibility overview

Sex: ALL

Age: 18 Years to 65 Years

Healthy volunteers: Yes

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria (Test Group):

* Voluntarily agreeing to participate in the study.
* Being over 18 years of age.
* Diagnosed with Multiple Sclerosis (MS) according to the 2017 McDonald criteria.
* Being able to communicate clearly and effectively.

Inclusion Criteria (Control Group):

* Voluntarily agreeing to participate in the study.
* Being over 18 years of age.
* Not having a diagnosis of Multiple Sclerosis (MS) according to the 2017 McDonald criteria.
* Being able to communicate clearly and effectively.

Exclusion Criteria (Test Group):

* Being under 18 years of age.
* Patients whose MS diagnosis is not yet definitive.
* Being pregnant or in the lactation (breastfeeding) period.
* Having received antibiotic treatment within the last 3 months.
* Having received periodontal treatment within the last 6 months.
* Patients undergoing radiotherapy or chemotherapy.

Exclusion Criteria (Control Group):

* Being under 18 years of age.
* Being diagnosed with Multiple Sclerosis (MS) according to the 2017 McDonald criteria.
* Being pregnant or in the lactation (breastfeeding) period.
* Having received antibiotic treatment within the last 3 months.
* Having received periodontal treatment within the last 6 months.
* Patients undergoing radiotherapy or chemotherapy.