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Isthmin-1 as a Biomarker of Disease Activity in Rheumatoid Arthritis: Correlation With Musculoskeletal Ultrasound Findings

NCT07374367

Not Yet RecruitingN/A

Sponsor: Amera Imam Abdel - Ghany Ahmed

Conditions: Disease Activity

The goal of this case control study is to detect serum isthmin-1 level in RA patient compered to healthy control . The main questions it aims to answer are: what is the serum isthmin-1 level in RA patient? what is the correlation between serum isthmin-1 and RA disease activity? what is the correlation between serum isthmin-1 level and MSUS finding in RA patients?

Eligibility overview

Sex: ALL

Age: 18 Years to 65 Years

Healthy volunteers: Yes

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

-Adult patients (≥18 years old) clinically diagnosed with rheumatoid arthritis according to the 2010 ACR/EULAR classification criteria.

Exclusion Criteria:

* Patients less than 18 years old.
* Patients with other autoimmune diseases.
* Participants with active infections, malignancies or diabetes.
* Recent hand surgery, trauma, deformity and neurological conditions affecting hand function