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Sponsor: University of Liege
Conditions: Multiple Sclerosis, Rehabilitation, Neuro-Degenerative Disease, Neurorehabilitation
Interventions: Eccentric training, Concentric training
Countries: Belgium
The project aims to optimise functional rehabilitation programmes for people with multiple sclerosis. Investigators are proposing eccentric cycling as a new exercise modality for treating these patients. Based on previous results in healthy subjects, investigators will attempt to define the optimal parameters of this new modality (in terms of duration, intensity, frequency, etc.). Investigators also aim to demonstrate the effectiveness of this training (compared to conventional training) in improving muscle function, functional capacity, perception of chronic fatigue, quality of life, physical condition, and neurological and cognitive function.
Sex: ALL
Age: 18 Years to 75 Years
Healthy volunteers: No
Study type: INTERVENTIONAL
Inclusion Criteria: * Diagnosis of multiple sclerosis * Multiple sclerosis: EDSS score \< 7 * Age under 75 years * Stable disease state * Written medical clearance authorizing participation * Legal adult status * Written informed consent, with demonstrated understanding of the consent form (via a few specific questions) * Ability to mobilize independently (e.g., transfers, walking) Exclusion Criteria: * One or more contraindications to physical activity * Significant comorbidities * Current hospitalization or undergoing changes in medication * Active flare-up
- Liège, Liège, Belgium