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Sponsor: George Washington University
Conditions: HIV
Interventions: Decision support tool, PrEP Delivery
Countries: United States
This project will explore the development of a personalized decision support tool to assist with pre-exposure prophylaxis (PrEP) initiation and persistence among patients identified in the emergency department (ED) and urgent care settings as PrEP eligible. First, the investigators will use a sequence of validated implementation science methodologies to develop and validate a decision support tool designed to optimize PrEP persistence by strengthening self-efficacy by addressing the multifaceted medical and social needs of the individual patient. The investigators will then test the preliminary effectiveness of this tool through a pilot stepped wedge implementation trial in two EDs and an urgent care in Baltimore, MD and Washington, DC among 120 PrEP eligible patients to determine PrEP initiation, linkage to care, persistence, and adherence rates.
Sex: ALL
Age: 18 Years to —
Healthy volunteers: Yes
Study type: INTERVENTIONAL
Inclusion Criteria: * English-speaking * Self-report being HIV negative (GWU sites) or are found to be HIV rapid test negative (JHH ED) * Medically stable ED/UC patients (defined as a triage category level 3, 4, 5 using Emergency Severity Index for ED patients only) Exclusion Criteria: * Currently taking PEP, PrEP, or present with signs/symptoms of acute HIV infection * Pregnant * Currently taking a nephrotoxic medication * Diagnosed with medical conditions that are contraindicated with use of TDF/FTC or TAF/FTC * Have a comorbid medical or psychiatric condition that would make PrEP adherence or ongoing follow-up care difficult * Admission to the hospital * Are in police custody/prisoner during the ED visit
- Washington D.C., District of Columbia, United States
- Baltimore, Maryland, United States