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Diagnostic Value of EBUS-Guided Transbronchial Mediastinal Cryobiopsy Versus Conventional Bronchoscopic Approaches for Stage I/II Sarcoidosis

NCT07246876

Active Not RecruitingNA

Sponsor: China-Japan Friendship Hospital

Conditions: Sarcoidosis, Pulmonary

Interventions: EBUS-TBNA-based sampling methods, EBUS-TBMC based sampling method

Countries: China

Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), combined with endobronchial biopsy (EBB) and/or transbronchial lung biopsy (TBLB), and endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) have high diagnostic yields for patients with sarcoidosis. However, a direct comparison between them has not been conducted. This randomized controlled trial aims to compare directly the diagnostic yield between EBUS-TBMC and EBUS-TBNA+EBB+TBLB in sarcoidosis.

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

1. Age ≥18years;
2. Patients with clinical and radiological suspicion of stage I or stage II sarcoidosis;
3. Fully informed of the purpose and method of the study

Exclusion Criteria:

1. Pathologically confirmed sarcoidosis, obvious organ involvement with the possibility of confirming granulomas using a minimally invasive diagnostic procedure;
2. Patients with medical contraindications to bronchoscopy procedures.

Locations (1)

Beijing, China