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Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)
Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)

NCT07204275

RecruitingPhase 2, Phase 3

Sponsor: Vertex Pharmaceuticals Incorporated

Conditions: Primary Membranous Nephropathy

Interventions: Povetacicept, Tacrolimus

Countries: United States, Australia, Brazil, China, Czechia, Germany, Hungary, Ireland

The purpose of this study is to evaluate the efficacy, safety, and tolerability of povetacicept in participants with primary membranous nephropathy (pMN).

Eligibility overview

Sex: ALL

Age: 18 Years to 75 Years

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria
Key Inclusion Criteria:

• Diagnosed with pMN with confirmatory historical biopsy. If no historical biopsy was performed that confirmed pMN, a biopsy can be performed during Screening to confirm eligibility

Key Exclusion Criteria:

• Hypersensitivity to investigational medicinal product or to any of its excipients

Other protocol defined Inclusion/Exclusion criteria will apply
Locations (111)
  • Montgomery, Alabama, United States
  • Surprise, Arizona, United States
  • Los Angeles, California, United States
  • Tarzana, California, United States
  • Arvada, Colorado, United States
  • Miami, Florida, United States
  • Orlando, Florida, United States
  • Winter Park, Florida, United States
  • Columbus, Georgia, United States
  • Lawrenceville, Georgia, United States
  • Boise, Idaho, United States
  • Hinsdale, Illinois, United States
  • Edina, Minnesota, United States
  • Roseville, Missouri, United States
  • Las Vegas, Nevada, United States
  • New York, New York, United States
  • Greenville, South Carolina, United States
  • Spartanburg, South Carolina, United States
  • El Paso, Texas, United States
  • Houston, Texas, United States
  • Houston, Texas, United States
  • San Antonio, Texas, United States
  • Salt Lake City, Utah, United States
  • Wauwatosa, Wisconsin, United States
  • Clayton, Australia
  • Concord, Australia
  • Kogarah, Australia
  • New Lambton Heights, Australia
  • Belo Horizonte, Brazil
  • Porto Alegre, Brazil
  • + 81 more on CT.gov