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Sponsor: Firat University
Conditions: Rheumatoid Arthritis (RA
Countries: Turkey (Türkiye)
In RA, joint structure is damaged due to destructive inflammation in the synovium. This condition negatively affects the patient's level of physical activity. As the patient becomes more immobile, their muscle mass and strength decrease and their aerobic capacity declines. One of the drug groups used in the pharmacological treatment of RA is anti-TNF-α drugs. The aim of this study is to investigate the effects of anti-TNF-α and non-TNF-α drug treatments on aerobic capacity, muscle strength, fatigue, cardiorespiratory risk factors, and disease activity in RA patients.
Sex: FEMALE
Age: 18 Years to 65 Years
Healthy volunteers: No
Study type: OBSERVATIONAL
Inclusion Criteria: * Diagnosed with RA according to the 2010 American College of Rheumatology (ACR-2010) criteria * Be between 18 and 65 years of age * Be literate * Have been using one of the anti-TNF-α or non-TNF-α drugs for a period of 1-3 years Exclusion Criteria: * Being pregnant or having a diagnosis of malignancy * Having a dysfunction that would limit physical activity (cycling for aerobic capacity assessment), such as severe neurological involvement, immobility, or incooperation * Having a regular exercise habit (reporting a habit of exercising 3 or more days per week) * Having another chronic disease * Having cardiac symptoms according to the New York Heart Association * Having mental problems that prevent participation in assessments
- Elâzığ, Turkey (Türkiye)