NCT lookup

Pull any trial record directly from ClinicalTrials.gov.

A Study to Evaluate Novel KarX and KarT Prototypes Versus the KarXT and KarX-EC Reference Following Single Doses, Explore the Effect of Food After Multiple Doses of Selected Prototypes, and Evaluate Alternative Formulations of KarX and KarXT Following Single and Multiple Ascending Doses

NCT07063342

RecruitingPhase 1

Sponsor: Bristol-Myers Squibb

Conditions: Healthy Volunteers

Interventions: Xanomeline/Trospium Chloride Capsule, Xanomeline Enteric Capsule, Trospium Chloride, Xanomeline MR, Xanomeline

Countries: United Kingdom

The purpose of this study is to evaluate novel KarX and KarT prototypes versus the KarXT and KarX-EC reference following single doses, to explore the effect of food after multiple doses of selected prototypes, and to evaluate alternative formulations of KarX and KarXT following single and multiple ascending doses in healthy adult participants.

Eligibility overview

Sex: ALL

Age: 18 Years to 55 Years

Healthy volunteers: Yes

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* BMI between 18.0 kg/m2 to 32.0 kg/m2, inclusive, at screening.
* Other protocol-defined Inclusion/Exclusion criteria apply.

Locations (1)

Nottingham, Nottinghamshire, United Kingdom