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Inclusion Criteria:

* Signed informed consent must be obtained prior to participation in the study
* Men and women aged ≥ 18 years and ≤ 75 years at Screening For RA only
* Diagnosis of rheumatoid arthritis
* Treatment failure of standard of care therapies
* Active disease For SjD only
* Diagnosis of Sjogren's disease
* Active disease

Exclusion Criteria:

* BMI at Screening of ≤17 or ≥ 40 kg/m2
* Clinically significant active, opportunistic, chronic or recurrent infection
* Sexually active males unwilling to use a condom during intercourse from the time enrollment
* Women of childbearing potential, unless they are using a highly effective method of contraception starting from the time of enrollment
* Female participants who are pregnant, breastfeeding or intending to conceive during the course of the study
* Inadequate organ function during screening
* History of lymphoproliferative disease or any known malignancy or history of malignancy
* History of bone marrow/hematopoietic stem cell or solid organ transplantation
* Any psychiatric condition or disability making compliance with treatment or informed consent impossible

Other protocol-defined inclusion/exclusion criteria may apply.

• Bordeaux, France
• Brest, France
• Le Kremlin-Bicêtre, France
• Lille, France
• Freiburg im Breisgau, Baden-Wurttemberg, Germany
• Göttingen, Lower Saxony, Germany
• Cologne, North Rhine-Westphalia, Germany
• Berlin, Germany
• Ulm, Germany
• Singapore, Singapore
• Barcelona, Spain
• Madrid, Spain