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Effect of Pulmonary Rehabilitation and Physical Activity on COVID-19 Long-Term Symptoms (PuReCOVID)

CompletedN/A

Sponsor: University of Parma

Conditions: COVID - 19

Interventions: Pulmonary Rehabilitation

Countries: Italy

This single-center, observational, longitudinal, retrospective and prospective study investigates the impact of Active Cycle of Breathing Technique (ACBT) and moderate daily physical activity on symptoms associated with long COVID, such as cough, dyspnea, and fatigue. The study aims to assess whether these interventions can moderately alleviate or resolve these symptoms and evaluate their potential association with small airway dysfunction (SAD), as measured by Impulse Oscillometry (IOS). The investigators will recruit 40 adult patients with long COVID who meet specific inclusion criteria. Participants will perform ACBT twice daily and complete at least 6000 steps per day for six weeks. The investigators will track clinical and lung function parameters, including spirometry, IOS, and exercise capacity.

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

* Male or female adults aged ≥18 years;
* Signed informed consent;
* Patients with long COVID
* Patients with or without ventilatory deficit (FEV1/FVC\>/≤70% and FVC\>/≤80%)
* Patients reporting at least one of the following symptoms: cough, dyspnea, and fatigue at 24 weeks post-infection

Exclusion Criteria:

* Patients with other coexisting chronic lung diseases (asthma, fibrosis, bronchiectasis, sarcoidosis, interstitial diseases, pulmonary hypertension)
* Active smoking patients

Locations (1)

Parma, Italy, Italy