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Sponsor: Universitair Ziekenhuis Brussel
Conditions: Multiple Sclerosis
Interventions: transcranial Direct Current Stimulation
Countries: Belgium
First the investigators will examine if the blood flow in the brain is different in patients with Multiple Sclerosis compared to healthy volunteers. HOW? \- The blood flow of the subjects is imaged by use of a special MRI-technique. Secondly, the investigators will examine if the blood flow can determine disease progression. HOW? - Multiple Sclerosis patients are asked for a follow-up visit after two years. The main goal is to understand the effect of transcranial Direct Current Stimulation (tDCS) on the cerebral blood flow. * Does tDCS result in a different blood flow, in which brain regions? * Is there a difference between healthy volunteers and Multiple Sclerosis patients? HOW? \- Participants get two session of tDCS. Before, during and after stimulation MRI scans are performed.
Sex: ALL
Age: 18 Years to —
Healthy volunteers: Yes
Study type: INTERVENTIONAL
Inclusion criteria - MS patient * EDSS ≥ 2 and EDSS ≤ 6.5 * Age ≥ 18 Exclusion criteria - MS patient * EDSS \> 6.5 * Incompatibility with MRI * Relapse within three months before the study and its use of corticosteroids * Disabling concomitant neuropsychiatric diseases * Chance of pregnancy, breastfeeding * Contraindications to tDCS Inclusion criteria - Healthy Volunteer • Age ≥ 18 Exclusion criteria - Healthy Volunteer * Incompatibility with MRI * Disabling concomitant neuropsychiatric diseases * Chance of pregnancy, breastfeeding * Contraindications to tDCS
- Brussels, Belgium
- Melsbroek, Belgium