NCT lookup

Pull any trial record directly from ClinicalTrials.gov.

Non-Invasive Neuromodulation for Upper Extremity Function in Spinal Cord Injury: A Crossover Trial

RecruitingPhase 2, Phase 3

Sponsor: University of Alberta

Conditions: Spinal Cord Injury Cervical

Interventions: Transcutaneous Cervical Spinal Cord Stimulation, Paired Corticospinal Motoneuronal Stimulation, Functional Task Practice

Countries: Canada

This study explores two promising therapies for restoring arm and hand function in people with chronic cervical spinal cord injury (SCI), a condition that affects independence and quality of life. It will compare transcutaneous spinal cord stimulation and paired corticospinal-motoneuronal stimulation, both combined with rehabilitation. Using a crossover design, participants will receive each therapy for two months, with a one-month washout period in between. Safety, effectiveness, and patient-reported outcomes like daily living ability and quality of life will be assessed, alongside changes in neural excitability. The results of this study may enable us to tailor treatments to individual needs, promoting personalized care and improved outcomes.

Eligibility overview

Sex: ALL

Age: 18 Years to 75 Years

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* Cervical (C2-C8) level SCI
* \> 9 months post-injury
* Traumatic SCI
* AIS A-D
* Stable dose of anti-spasmodics

Exclusion Criteria:

* individuals with injury to the nervous system other than to the spinal cord
* pregnant

Locations (1)

Edmonton, Alberta, Canada