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Transcranial Magnetic Stimulation for Methamphetamine Use Disorder in PLWH

CompletedNA

Sponsor: Gopalkumar Rakesh

Conditions: Methamphetamine Use Disorders, HIV

Interventions: intermittent theta burst stimulation (iTBS), continuous theta burst stimulation (cTBS), Sham TMS

Countries: United States

The purpose of this study is to learn more about how accelerated theta burst stimulation affects methamphetamine craving and brain activity. Theta burst stimulation is a unique transcranial magnetic stimulation (TMS) paradigm that is efficient and potent.

Eligibility overview

Sex: ALL

Age: 18 Years to 65 Years

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* Adults in the age group 18-65 years
* Able to read and understand English
* Able to provide informed consent
* Diagnosed with HIV
* History of current or previous Methamphetamine Use Disorder
* Endorse craving for methamphetamine
* Demonstrate an attentional bias for methamphetamine

Exclusion Criteria:

* Traumatic brain injury
* h/o seizure disorder
* h/o or current diagnosis of schizophrenia
* intracranial metal shrapnel
* previous adverse effects with TMS
* sub-threshold consistency while performing behavioral tasks
* lack of attentional bias to methamphetamine cues
* a positive pregnancy test for female participants
* abnormal brain MRI

Locations (1)

Lexington, Kentucky, United States