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Hormonal Control of Energy and Macronutrient Intake in Obesity (MEMORY)

CompletedNA

Sponsor: Steno Diabetes Center Copenhagen

Conditions: Obesity, Normal Weight, Overweight

Interventions: High protein liquid test meal, High carbohydrate liquid test meal

Countries: Denmark

The overall aim of the MEMORY study is to examine the concept of 'food memory' - how specific macronutrient compositions influence subsequent food preference and intake, and whether this differs across the BMI range from normal weight to obesity.

Eligibility overview

Sex: ALL

Age: 18 Years to 45 Years

Healthy volunteers: Yes

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* Age 18-45 years
* For women: Regular menstruation
* BMI-range 18.5-39.9 kg/m\^2

Exclusion Criteria:

* Not able or willing to eat or drink the test meals because of e.g., allergy or intolerance
* Daily smoking
* For women: Pregnancy / planned pregnancy (within the study period) / lactating
* Self-reported history of an eating disorder
* Self-reported weight change (kg) within two months prior to inclusion
* HbA1c ≥48 mmol/mol
* Treatment with antidepressants
* Alcohol/drug abuse or in treatment with disulfiram (antabus) at time of inclusion
* Uncontrolled medical issues including but not limited to cardiovascular pulmonary, rheumatologic, hematologic, oncologic, infectious, gastrointestinal, or psychiatric disease; diabetes or other endocrine disease; immunosuppression
* Current treatment with medication which significantly affect appetite or energy balance (e.g., GLP-1 receptor agonists)
* Bariatric surgery
* Unable to understand the informed consent and the study procedures
* Concomitant participation in intervention studies
* Participant's withdrawal of the informed consent
* Other safety concerns - judged by the investigator

Locations (1)

Herlev, Denmark, Denmark