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A Study Conducted to Evaluate the Conjunctiva and Tenon's Capsule Status of Healthy Subjects and in Participants With Neovascular Age-related Macular Degeneration (nAMD)/Diabetic Macular Edema (DME)

NCT06723288

CompletedN/A

Sponsor: Hoffmann-La Roche

Conditions: Neovascular Age-related Macular Degeneration, Diabetic Macular Edema

Countries: Spain

The purpose of this study is to obtain conjunctiva and tenon's capsule thickness measurements in vivo using spectral domain-optical coherence tomography (SD-OCT) in participants with nAMD/DME and age-matched healthy subjects.

Eligibility overview

Sex: ALL

Age: 45 Years to —

Healthy volunteers: Yes

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

For nAMD/DME participants:

\- Diagnosis of nAMD/DME

For healthy subjects:

\- Normal visual function

Exclusion Criteria:

* Current or past treatment for glaucoma (only for healthy subjects)
* Dry eye disease except those treated only with artificial tears
* Ocular hypertension treated with hypotensive drugs
* Pterygium
* Strabismus
* Previous ocular surgery except cataract surgery
* Cataract surgery with scleral incision
* Current contact lens wearers
* Myopia with more than 6 diopters
* Corneal transplant
* History of ocular surface inflammation
* Active or recent conjunctivitis infection
* Pregnancy
* Participant who has already received an IVT injection in the superotemporal quadrant (only for nAMD/DME participants)

Locations (20)

L'Hospitalet de Llobregat, Barcelona, Spain
San Cugat Del Valles, Barcelona, Spain
Majadahonda, Madrid, Spain
Pamplona, Navarre, Spain
Oviedo, Principality of Asturias, Spain
Burjassot, Valencia, Spain
Barcelona, Spain
Barcelona, Spain
Barcelona, Spain
Barcelona, Spain
Córdoba, Spain
Madrid, Spain
Madrid, Spain
Madrid, Spain
Madrid, Spain
Seville, Spain
Seville, Spain
Valencia, Spain
Valencia, Spain
Valladolid, Spain