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Resistance Training and Corticospinal Excitability in Multiple Sclerosis

RecruitingNA

Sponsor: University of Aarhus

Conditions: Multiple Sclerosis

Interventions: Progressive resistance training

Countries: Denmark

The goal of the present study is to investigate effects of progressive resistance training on central nervous system functioning (corticospinal excitability (CSE)) and walking capacity in persons with multiple sclerosis (pwMS). A total of 54 pwMS will be enrolled and randomized into 1 of 3 groups: high dose resistant training (RT), low dose RT, and waitlist control.

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* Age ≥ 18 years
* MS diagnosis according to the McDonald diagnostic criteria
* Shows impairments in walking capacity
* Ability to self transport to test and exercise

Exclusion Criteria:

* Pregnancy
* Neurological or other comorbidities that affects the nervous system
* Relapse within the past 2 months
* Pacemaker or metallic implants
* Hypertension (medically unregulated)
* Participation in structured RT over the past 3 months (≥ 2 sessions/week).

Locations (2)

Aarhus, Central Jutland, Denmark
Copenhagen, Copenhagen N, Denmark