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Sponsor: Johns Hopkins University
Conditions: Polypharmacy, Alzheimer's Disease and Related Dementias, Mild Cognitive Impairment
Interventions: Pharmacist-led deprescribing intervention
Countries: United States
The goal of this clinical trial is to test the effectiveness of a pharmacist-led, primary care-based de-prescribing intervention for people living with dementia (PLWD) and the person's care partners. The intervention consists of the following strategies: 1) a de-prescribing educational brochure designed to activate the patient and care partner; 2) a single telehealth visit in which an embedded clinical pharmacist discusses the benefits and harms of the patient's medications with the patient and care partner in the context of the person's goals and preferences; and 3) pharmacist-PCP communication in which the pharmacist provides tailored de-prescribing recommendations designed to be useful and actionable for the PCP. The investigators will compare the intervention group with the waitlist control group to see if there is a difference in the primary outcome, the proportion of patients who deprescribe at least one medication by 3 months.
Sex: ALL
Age: 65 Years to —
Healthy volunteers: Yes
Study type: INTERVENTIONAL
Inclusion Criteria: * Age ≥65 years * Diagnosis of dementia from International Classification of Diseases (ICD-10) visit codes or from the EHR problem list * Five or more medications * Only active patients, defined as having \>1 visit to the primary care clinic within the past year will be included Care partners: * Family or other companions \>21 years old who regularly help the patient manage medications. Exclusion Criteria: * As the pragmatic trial will be based on primary care, individuals residing in long-term care facilities or enrolled in hospice will be excluded. * Participants must hear well enough to communicate by telephone in English.
- Baltimore, Maryland, United States