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COld Exposure With Controlled BReathing And Meditation in Patients With Multiple Sclerosis (COBRAMS)
COld Exposure With Controlled BReathing And Meditation in Patients With Multiple Sclerosis (COBRAMS)

NCT06280573

UnknownNA

Sponsor: Comenius University

Conditions: Multiple Sclerosis

Interventions: Wim Hoff method

Countries: Slovakia

The goal of this interventional study is to test the effect of the anti-inflammatory and neuroprotective effects of this supplementary training program that includes breathing exercises, cold exposure, and meditation in patients diagnosed with multiple sclerosis. Researchers will compare the effect to control groups of MS patients without intervention.

Eligibility overview

Sex: ALL

Age: 18 Years to 55 Years

Healthy volunteers: Yes

Study type: INTERVENTIONAL

Eligibility criteria
Inclusion Criteria:

* RRMS diagnosed according to the official 2020 McDonald's criteria,
* age 18-55 years,
* MS duration up to 10 years,
* EDSS 1.0-5.5,
* willingness to participate

Exclusion Criteria:

* relapse or corticosteroid treatment within 3 months prior to study enrollment
* severe/unstable comorbidity
Locations (1)
  • Bratislava, Slovakia