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Sponsor: Comenius University
Conditions: Sclerosis, Multiple
Interventions: Dance classes
Countries: Slovakia
The evidence suggests that multiple sclerosis (MS) induces a decline in motor and cognitive function and provokes a shift in gut microbiome composition in patients. Therefore, the purpose of this study is to explore the effect of a 12-week dance class training program on the gut microbiota composition, motor function, and cognitive function of patients with MS. The investigators will also study the following: * The impact of organised physical activity on quality of life * The impact of organised physical activity on body composition and metabolic parameters (e.g., insulin sensitivity, lipid profile, ect.) * The impact of organised physical activity on physical fitness (e.g., VO2max, Power, ect.)
Sex: ALL
Age: 30 Years to 50 Years
Healthy volunteers: No
Study type: INTERVENTIONAL
Inclusion Criteria: * patients with multiple sclerosis, diagnosed according to official diagnostic criteria according to McDonald 2010 * Consent ability and written consent * The expanded disability status scale (EDSS) \<5.5 * age 30 - 50 Exclusion Criteria: * serious comorbidities including psychiatric diseases * Significant cognitive impairment, clinically relevant or progressive disease (e.g., liver, kidney, cardiovascular system, respiratory tract, vascular system, brain, metabolism, thyroid) that could affect the course of the study * Clinically relevant addiction or substance abuse disorder (defined as alcohol, drug and drug abuse) * Nicotine consumption of \> 5 cigarettes per day and no willingness to stop consumption during therapeutic fasting. * Simultaneous participation in an interventional study or participation in an interventional study in the last two months before study inclusion * Malignant disease * Insufficient mental possibility of cooperation Eating disorder
- Bratislava, Slovakia