NCT lookup

Pull any trial record directly from ClinicalTrials.gov.

5-SENSE Score Validation Study

Enrolling By InvitationN/A

Sponsor: Duke University

Conditions: Epilepsy Intractable

Interventions: Stereoelectroencephalography (SEEG)

Countries: United States, Australia, Austria, Canada, Czechia, Denmark, France, Germany

The purpose of this study is to assess how well a new scoring system called the 5-SENSE score can predict where seizures start in the brain using Stereoelectroencephalography (SEEG). The 5-SENSE Score is a 5-point score based on routine presurgical work-up, designed to assist in predicting whether SEEG can identify a focal seizure onset zone, thereby sparing patients the risk of undergoing this invasive diagnostic procedure.

Eligibility overview

Sex: ALL

Age: 15 Years to —

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

* patients aged 15 years or older in whom no direct surgical approach can be offered and who are discussed in the multidisciplinary team discussion
* availability of complete non-invasive presurgical work-up (including high-resolution MRI according to the in-center epilepsy protocol, video-telemetry with the recording of a minimum of one habitual clinic and EEG seizure, available as original files for review)

Exclusion Criteria:

* no telemetry/scalp EEG in center
* no protocol MRI in center
* subdural/GRID electrodes

Locations (19)

Gainesville, Florida, United States
Chicago, Illinois, United States
Durham, North Carolina, United States
Pittsburgh, Pennsylvania, United States
Melbourne, Victoria, Australia
Brisbane, Australia
Melbourne, Australia
Salzburg, Austria
Dalhousie, Nova Scotia, Canada
London, Ontario, Canada
Brno, Czechia
Aarhus, Denmark
Grenoble, France
Marseille, France
Freiburg im Breisgau, Germany
Kyoto, Japan
Bucharest, Romania
Valencia, Spain
Lausanne, Switzerland