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Molecular Characterization of Penile Cancers in Developing Countries

CompletedN/A

Sponsor: Latin American Cooperative Oncology Group

Conditions: Penile Squamous Cell Carcinoma

Countries: Brazil

This study explores penile squamous cell carcinoma (PSCC) in Brazil, a rare cancer associated with factors like poor hygiene and HPV infection, using next-generation sequencing to investigate its genomic profiles in 24 deceased patients with advanced PSCC.

Eligibility overview

Sex: MALE

Age: 18 Years to —

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

* Men ≥ 18 years of age;
* Diagnosis of locally advanced or metastatic squamous-cell penile carcinoma;
* Have received at least one treatment for advanced disease (surgery, radiotherapy and/or chemotherapy);
* Available representative tumor block of formalin-fixed and paraffin-embedded (FFPE) archive, from primary or metastasis;
* Patients must be already deceased at time of data collection.

Exclusion Criteria:

* Patients without medical record available (lost, empty or irretrievable clinical information).

Locations (3)

Fortaleza, Ceará, Brazil
São Luís, Maranhão, Brazil
Porto Alegre, Rio Grande do Sul, Brazil