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Prospective Cohort for Tumor Bed Boost Radiotherapy in HER2 Positive Breast Cancer

RecruitingN/A

Sponsor: Samsung Medical Center

Conditions: Breast Cancer

Interventions: Whole breast irradiation +/- tumor bed boost

Countries: South Korea

The purpose of this study is to analyze treatment outcomes related to tumor bed boost of postoperative radiation therapy in patient with HER2+ breast cancer who underwent breast conserving surgery. The main questions it aims to answer are: * 7-year ipsilateral breast tumor recurrence * 7-year disease-free survival * 7-year locoregional recurrence * 7-year overall survival * Adverse events of radiation therapy Participants will be assessed by multi-dimensional methods after radiation therapy: * Assessment for the disease status (disease-free or recurrence) including physical and radiologic examination * Assessment for the adverse events according to CTCAE version 5.0

Eligibility overview

Sex: FEMALE

Age: 19 Years to —

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

* Female patients with age minimum 19
* Pathological confirmation of HER2+ invasive breast cancer
* Eastern Cooperative Oncology Group performance status 0-2
* Informed consent of the participant

Exclusion Criteria:

* Pathological confirmation of ductal carcinoma in situ of the breast
* Previous history of radiation therapy to ipsilateral breast

Locations (1)

Seoul, Seoul, South Korea