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South Africa Smoking Cessation and Engagement in HIV/TB Care Care

RecruitingNA

Sponsor: Massachusetts General Hospital

Conditions: HIV Infections, Tuberculosis, Smoking Cessation

Interventions: QUIT-AD, Enhanced Treatment as Usual

Countries: South Africa

The purpose of this study is to integrate elements from existing interventions developed by our team into a single intervention (QUIT-AD), designed to improve smoking cessation and favorable HIV/TB treatment outcomes among individuals with HIV and/or TB in Cape Town, South Africa. If feasibility, acceptability, and preliminary efficacy are demonstrated, the intervention will be ready for large-scale effectiveness/implementation testing. This program will has the potential to dramatically improve public health by increasing the smoking quit rate and facilitating favorable HIV/TB treatment outcomes among patients with HIV and/or TB in resource limited South African settings.

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

1. Aged 18 or older
2. Willing and able to provide written informed consent
3. Living with HIV, confirmed via medical record, and on antiretroviral therapy (ART) AND/OR within 1 month of initiating or reinitiating TB treatment; positive GeneXpert test or sputum culture

(5) Daily smoker operationalized as \> 5 cigarettes per day, (6) Motivation (\> 5/10) to quit smoking or \> 24 hour quit past yr

Exclusion Criteria:

1. Habitual use of other tobacco products
2. Current interfering untreated/unstable mental health condition (e.g., psychosis, bipolar dx)
3. Current use of non-study pharmacotherapy for smoking cessation,
4. Cognitive Behavioral Therapy for smoking cessation initiated within the past year,
5. Diagnosed with extra-pulmonary or drug resistant (MDR or XDR) TB based upon chart review

Locations (1)

Rondebosch, South Africa