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Identifying and Characterizing Preclinical MS

RecruitingN/A

Sponsor: Yale University

Conditions: Multiple Sclerosis

Interventions: biological samples

Countries: United States

The purpose of this research study is to try and identify risk factors and biologic changes that suggest that someone may go on to develop multiple sclerosis before a person has shown any symptoms of the disease.

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: Yes

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

* Age 18+
* Having one or more risk factors for multiple sclerosis, including one or more of the below:

  * Individuals known to have a radiologically isolated syndrome
  * Individuals with a family history of multiple sclerosis (first degree family member)
  * Individuals with personal risk factors, which are known to include smoking, obesity, Epstein Barr virus infections, Vitamin D deficiency, genetic risk score

Exclusion Criteria:

* Currently pregnant
* Diagnosis of multiple sclerosis or any ongoing, systemic autoimmune disease
* Ongoing treatment with immunosuppressive medications

Locations (1)

North Haven, Connecticut, United States