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Real Life Lipid Management in Hospitals Not Participating in PENELOPE Trial - Control Population for PENELOPE
Real Life Lipid Management in Hospitals Not Participating in PENELOPE Trial - Control Population for PENELOPE

NCT05659888

CompletedN/A

Sponsor: Clinical Operations WCN B.V.

Conditions: Atherosclerotic Cardiovascular Disease, STEMI, Non STEMI

Countries: Netherlands

Guideline recommended evidence-based clinical care correlates with improved patient outcomes. In real life care, however, adherence to guideline recommendations remains suboptimal. In real life, patients may receive suboptimal treatment and as a result treatment targets are not always met. To support and improve secondary prevention for cardiovascular disease, PENELOPE and PENELOPE-CTRL are designed to support guideline implementation on lipid management and provide valuable feedback to care-givers on real world data.

Eligibility overview

Sex: ALL

Age: 18 Years to 70 Years

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria
Inclusion Criteria:

* Age \>18 and ≤70 years
* Alive at hospital discharge after admission for (N)STEMI between 1-1-2019 and 31-08-2020
* Planned for follow-up at a participating PENELOPE CTRL site
* History of T2DM and/or history of ASCVD defined as either one of:

  * cerebrovascular disease/ event: transient ischemic attack, cerebral infarction, amaurosis fugax, retinal infarction
  * Coronary artery disease/ event: unstable angina pectoris, MI, ACS, coronary revascularization (coronary angioplasty or surgical procedure for coronary bypass)
  * Peripheral artery disease (symptomatic and documented obstruction of a distal extremity artery or surgical intervention (percutaneous transluminal angioplasty, bypass or amputation)

Exclusion Criteria:

* Pregnant and lactating women
* Participation in lipid modifying drug trials up to two years after index cardiovascular event
Locations (13)
  • Alkmaar, Netherlands
  • Delft, Netherlands
  • Deventer, Netherlands
  • Emmen, Netherlands
  • Hardenberg, Netherlands
  • Helmond, Netherlands
  • Leiden, Netherlands
  • Meppel, Netherlands
  • Nijmegen, Netherlands
  • The Hague, Netherlands
  • The Hague, Netherlands
  • Utrecht, Netherlands
  • Veldhoven, Netherlands