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Rhythmic Auditory Stimulation on Upper-limb Movements in PD Patients

CompletedNA

Sponsor: The Hong Kong Polytechnic University

Conditions: Acoustic Stimulation, Parkinson Disease, Movement, Abnormal, Bradykinesia, Arm

Interventions: Upper-limb movement training with the aid of RAS, Upper-limb movement training without the aid of RAS

Countries: China

The goal of this clinical trial is to examine effects of training involving rhythmic auditory stimulation (RAS) on upper-limb movements and functions in patients with Parkinson's disease (PD). This study employed a 21-day randomized controlled trial design to evaluate the efficacy of upper-limb training involving RAS on upper-limb function and neural activity in PD patients. The RAS group showed sustained improvements at one-month follow-up.

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* idiopathic PD diagnosed by a neurologist based on the Movement Disorders Society clinical diagnostic criteria;
* the Hoehn and Yahr stage is 2 or 3, meaning that bilateral movement problems or combination with mild postural instability;
* a score of Montreal Cognitive Assessment is equal to or higher than 21 to ensure that they understand experimental instructions;
* a score of Edinburgh Handedness Inventory is above 60 to ensure that they are right-handed;
* types and doses of medications remain unchanged in the past month right before participation.

Exclusion Criteria:

* the presence of medical conditions or diseases that may affect hand movements, vision, or hearing based on self-report.

Locations (1)

Wuhan, Hubei, China