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The Value of Repeated BIOMarker Measurements During an SBT to Predict EXtubation Failure in ICU Patients

CompletedN/A

Sponsor: Henrik Endeman

Conditions: Weaning Failure, Mechanical Ventilation, Spontaneous Breathing Trial, Extubation Failure

Countries: Netherlands

The Value of Repeated BIOMarker Measurements During an SBT to Predict EXtubation Failure in Mechanically Ventilated ICU Patients

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

* Aged ≥18 years
* Mechanically ventilated for more than 48 hours
* Fulfilling readiness-to wean criteria
* Written informed consent from the patient or his/her legal representative

Exclusion Criteria:

* Patients with risk factors for laryngeal oedema and a negative cuff leak test (indicating upper airway obstruction with need for steroid treatment)
* Planned replacement of the endotracheal tube for a tracheostomy
* Terminal illness

Locations (1)

Rotterdam, South Holland, Netherlands