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Understanding Motivation in Parkinson's Patients Through Neurophysiology
Understanding Motivation in Parkinson's Patients Through Neurophysiology

NCT05065151

RecruitingNA

Sponsor: University of California, San Francisco

Conditions: Parkinson Disease, Deep Brain Stimulation, Motivation

Interventions: Stimulation on, Stimulation off, Decision Making Task

Countries: United States

The study aims to better understand motivation and value-based decision-making in Parkinson's patients through neurophysiology using Medtronic's Percept DBS device. By combining behavioral tasks with neural recordings, the study seeks to uncover how DBS affects motivation, particularly in relation to effort, reward, and timing.

Eligibility overview

Sex: ALL

Age: 18 Years to

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria
Inclusion Criteria:

* Has Parkinson's Disease or Dystonia
* Has Medtronic Percept or RC+S DBS device implanted in either GPI or STN
* Has DBS device implanted either bilaterally or unilaterally
* Male or female
* More than 1 month post-DBS surgery

Exclusion Criteria:

* Severe cognitive impairments
* Has MOCA score below 20
* Pregnancy
* Age less than 18 years old
Locations (1)
  • San Francisco, California, United States