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Role of Mechanical Load on Metabolic Exercise Adaptations in Response to Weight Loss in Obese Adolescents: The POWELL Study

NCT04902001

CompletedNA

Sponsor: University Hospital, Clermont-Ferrand

Conditions: Pediatric Obesity

Interventions: Multidisciplinary weight loss

Countries: France

While interdisciplinary weight loss intervention have been shown successful among adolescents with obesity, a weight regain is most of the time observed within the following weeks or months. The aim of the present project will be to better identify the independent role played by both the metabolic and mechanical load and their modification during weight loss, on the energy expenditure and energy metabolism of adolescents with obesity.

Eligibility overview

Sex: ALL

Age: 12 Years to 16 Years

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* being aged 12-16 years old
* no contraindication to physical exercise
* no cardiovascular disease
* BMI above the 97th percentile
* candidate to a weight loss intervention

Exclusion Criteria:

* surgery and medical conditions preventing them to perform the intervention
* Weight loss during the previous 6 months
* medication that could interfere with energy metabolism.
* pregnancy
* regular tobacco and alcool use

Locations (1)

Clermont-Ferrand, France