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Characterization in 18F-FDG PET-CT of Brain and Lung Lesions in Subjects With a History of Severe COVID-19
Characterization in 18F-FDG PET-CT of Brain and Lung Lesions in Subjects With a History of Severe COVID-19

NCT04764721

CompletedNA

Sponsor: Central Hospital, Nancy, France

Conditions: Covid-19

Interventions: 18F-FDG PET-CT

Countries: France

Patients with Covid-19 (Coronavirus disease 19) may experience multiple neurological symptoms . 18F-FDG PET-CT ( Positons EmissionTomography coupled with a Computer Tomography with flurodesoxyglucose labelled with fluor 18), which reflects neuronal glycolytic metabolism, shows early variations in neuronal function. Moreover the tropism of Covid-19 is essentially pulmonary and the hypothesis of this study is with 18F-FDG PET-CT it's possible to study the relationship between cerebral metabolism and the metabolism of pulmonary lesions following Covid-19 infection.

Eligibility overview

Sex: ALL

Age: 18 Years to 65 Years

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria
Inclusion Criteria:

* Patients aged between 18 and 65 years
* Patient included in the Neurocog-Covid study (i.e. presenting a cognitive disorder that has been objectified on the neuropsychological assessment and having to undergo a cerebral MRI),
* Patient who has received full information about the organization of the research and has given written informed consent (or a third person, independent of the investigator and sponsor, in the case of literacy disability),
* Patient affiliated to or beneficiary of a social security plan

Exclusion Criteria:

* Women of childbearing age who do not have effective contraception.
* Pregnant woman or nursing mother.
* Persons referred to in Articles L. 1121-5, L. 1121-7 and L1121-8 of the Public Health Code.
* Persons deprived of liberty by a judicial or administrative decision, persons undergoing psychiatric care pursuant to articles L. 3212-1 and L. 3213-1
* Contraindication to perform 18F-FDG PET-CT
* Patients with a history of pre-Covid-19 psychiatric or chronic illness
* Persons referred to in Articles L. 1121-5, L. 1121-7 and L1121-8 of the Public Health Code.
Locations (1)
  • Vandœuvre-lès-Nancy, France