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Study of AT-527 in Healthy Subjects (R07496998)

NCT04711187

CompletedPhase 1

Sponsor: Atea Pharmaceuticals, Inc.

Conditions: Healthy Volunteer Study

Interventions: AT-527 Formulation 1, Placebo Comparator, AT-527 Formulation 2

Countries: Canada

This study will assess the safety, tolerability and pharmacokinetics (PK) of AT-527 in healthy subjects.

Eligibility overview

Sex: ALL

Age: 18 Years to 65 Years

Healthy volunteers: Yes

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* Must agree to use two methods of birth control from Screening through 90 days after administration of the last dose of study drug
* Females must have a negative pregnancy test at Screening and prior to dosing
* Minimum body weight of 50 kg and body mass index (BMI) of 18-32 kg/m2
* Willing to comply with the study requirements and to provide written informed consent

Exclusion Criteria:

* Pregnant or breastfeeding
* Infected with hepatitis B virus, hepatitis C virus, HIV or COVID-19
* Abuse of alcohol or drugs
* Use of other investigational drugs within 28 days of dosing
* Other clinically significant medical conditions or laboratory abnormalities

Locations (1)

Montreal, Quebec, Canada