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Sponsor: University of Aberdeen
Conditions: Covid19, Pulmonary Embolism
Interventions: Exposure: Positive COVID-19 infection, Exposure: Negative COVID-19 infection
Countries: United Kingdom
The World Health Organization (WHO) declared the 2019 novel coronavirus (COVID-19) a pandemic on March 11, 2020. As of 19 July 2020, there have been 14.3 million confirmed cases and over 600,000 confirmed deaths. Up to 14% of infected patients develop interstitial pneumonia, which may evolve to acute respiratory distress syndrome. COVID-19 associated pulmonary arterial microthrombosis and coagulopathy has prompted physicians to implicate pulmonary embolism (PE) as a potential cause for acute respiratory deterioration. Literature review reveals few studies of varying size, quality and design. Recent meta-analysis reports venous thromboembolism in approximately 20% of COVID-19 patients. There has yet to be a case-controlled study which proves and quantifies the associated between COVID-19 and PE.Confirming and quantifying this association has numerous clinical implications for the treatment of critically unwell patients with COVID-19 infection. For example, clinicians will be more inclined to investigate and treat sudden deteriorations with the knowledge that pulmonary embolism is the commonest cause for said deteriorations.
Sex: ALL
Age: 16 Years to —
Study type: OBSERVATIONAL
Inclusion Criteria: -Patients who had a CT pulmonary angiogram at NHS Grampian between 3rd March and 20th June 2020. Exclusion Criteria: * Patients with no COVID-19 RT-PCR test done within 7 days of the CT pulmonary angiogram or the same clinical episode. * Duplicate CT pulmonary angiograms. * Patients who are already known to have a pulmonary embolism. * Patients who had radiologically inadequate CT pulmonary angiograms. * Patients younger than 16 years old. * Patients who have incomplete or unavailable notes.
- Aberdeen, United Kingdom