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Observational Study of Durvalumab in Patients With Non-small-cell Lung Cancer in the United Kingdom
Observational Study of Durvalumab in Patients With Non-small-cell Lung Cancer in the United Kingdom

NCT04667312

CompletedN/A

Sponsor: AstraZeneca

Conditions: Non-Small Cell Lung Cancer NSCLC

Interventions: Durvalumab

Countries: United Kingdom

This is a retrospective observational research study to describe the characteristics and real-world clinical outcomes of patients with locally advanced, unresectable Stage III non-small cell lung cancer receiving durvalumab in the United Kingdom (the CODAK study). Physicians who have treated patients who have locally advanced, unresectable Stage III NSCLC with durvalumab will be requested to recruit patients to have their clinical data abstracted from their clinical records in line with local laws. Data from this study will provide UK-specific real-world data on patients receiving durvalumab through the Early Access Programme (EAP) or post-reimbursement.

Eligibility overview

Sex: ALL

Age: 18 Years to

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria
Inclusion Criteria:

* Patient has documented diagnosis of locally advanced, unresectable Stage III NSCLC
* Patient has received platinum-based CRT and received ≥1 dose of durvalumab
* Patient was initiated on durvalumab (index event) between 1st September 2017 and 31st December 2019 via the EAP or non-EAP
* Patient was aged ≥18 years at durvalumab initiation

Exclusion Criteria:

* Patients who participated in the PACIFIC-R study
* Participation in any clinical study with an investigational product at the time of durvalumab initiation or during the observational period
Locations (10)
  • Canterbury, United Kingdom
  • Cardiff, United Kingdom
  • Harrogate, United Kingdom
  • Leeds, United Kingdom
  • London, United Kingdom
  • London, United Kingdom
  • Manchester, United Kingdom
  • Portsmouth, United Kingdom
  • Taunton, United Kingdom
  • Truro, United Kingdom